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10.1097/MD.0000000000021334

http://scihub22266oqcxt.onion/10.1097/MD.0000000000021334
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32702930!7373607!32702930
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suck abstract from ncbi


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pmid32702930      Medicine+(Baltimore) 2020 ; 99 (29): e21334
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  • Coronavirus disease 2019 (COVID-19) in pregnancy: 2 case reports on maternal and neonatal outcomes in Yichang city, Hubei Province, China #MMPMID32702930
  • Zheng T; Guo J; He W; Wang H; Yu H; Ye H
  • Medicine (Baltimore) 2020[Jul]; 99 (29): e21334 PMID32702930show ga
  • RATIONALE: The outbreak of coronavirus disease 2019 (COVID-19) in 2019 has become a global pandemic. It is not known whether the disease is associated with a higher risk of infection in pregnant women or whether intrauterine vertical transmission can occur. We report 2 cases of pregnant women diagnosed with COVID-19. PATIENT CONCERNS: In all of Yichang city from January 20, 2020, to April 9, 2020, only 2 pregnant women, who were in the late stage of pregnancy, were diagnosed with COVID-19; one patient was admitted for fever with limb asthenia, and the other patient was admitted for abnormal chest computed tomography results. DIAGNOSES: Both pregnant women were diagnosed with COVID-19. INTERVENTIONS: After the medical staff prepared for isolation and protection, the 2 pregnant women quickly underwent cesarean sections. A series of tests, such as laboratory, imaging, and SARS-CoV-2 nucleic acid examinations, were performed on the 2 women with COVID-19 and their newborns. OUTCOMES: One of the 2 infected pregnant women had severe COVID-19, and the other had mild disease. Both babies were delivered by cesarean section. Both of the women with COVID-19 worsened 3 to 6 days after delivery. Chest computed tomography suggested that the lesions due to SARS-CoV-2 infection increased. These women began to exhibit fever or reduced blood oxygen saturation again. One of the 2 newborns was born prematurely, and the other was born at full term. Neither infant was infected with COVID-19, but both had increased prothrombin time and fibrinogen, lactate dehydrogenase, phosphocreatine kinase, and creatine kinase isoenzyme contents. LESSONS: SARS-CoV-2 infection was not found in the newborns born to the 2 pregnant women with COVID-19, but transient coagulation dysfunction and myocardial damage occurred in the 2 newborns. Effective management strategies for pregnant women with COVID-19 will help to control the outbreak of COVID-19 among pregnant women.
  • |Adult[MESH]
  • |Asthenia/etiology[MESH]
  • |Betacoronavirus/*genetics/isolation & purification[MESH]
  • |COVID-19[MESH]
  • |Cesarean Section/methods[MESH]
  • |China/epidemiology[MESH]
  • |Coronavirus Infections/*diagnosis/drug therapy/*virology[MESH]
  • |Disease Outbreaks/prevention & control[MESH]
  • |Female[MESH]
  • |Fever/etiology[MESH]
  • |Humans[MESH]
  • |Infant, Newborn/blood/metabolism[MESH]
  • |Infectious Disease Transmission, Vertical/prevention & control[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnosis/drug therapy/*virology[MESH]
  • |Pregnancy[MESH]
  • |Pregnancy Complications, Infectious/epidemiology/virology[MESH]
  • |Pregnancy Outcome/epidemiology[MESH]
  • |Premature Birth/epidemiology[MESH]
  • |SARS-CoV-2[MESH]
  • |Thorax/diagnostic imaging[MESH]


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