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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Res+Sq 2021 ; ä (ä): ä Nephropedia Template TP
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Association between air pollution in Lima and the high incidence of COVID-19: findings from a post hoc analysis #MMPMID32702735
BACKGROUND: Corona virus disease (COVID-19) originated in China in December 2019. Thereafter, a global logarithmic expansion of the cases has occurred. Some countries have a higher rate of infections despite of early implementation of quarantine. Air pollution could be related to the high susceptibility to SARS-CoV-2 and the associated case-fatality rates (deaths/cases*100). Lima, Peru has the second highest incidence of COVID-19 in Latin America, and it is also one of the cities with highest levels of air pollution in the Region. METHODS: This study investigated the association of the levels of PM(2.5) exposure in the previous years (2010-2016) in 24 districts of Lima with the positive-cases, deaths and case-fatality rates of COVID-19. Multiple Linear regression was used to evaluate this association controlled by age, sex, population density and number of food markets per district. The study period was from March 6 to June 12, 2020. RESULTS: There were in Lima 128,700 SARS-CoV-2 positive cases, and 2,382 deaths due to COVID-19. The case-fatality rate was 1.93%. Previous exposure to PM(2.5) (years 2010-2016) was associated with number of Covid-19 positive-cases (beta = 0.07; 95% CI: 0.034-0.107) and deaths (beta = 0.0014; 95% CI: 0.0006-0.0.0023), but not with case-fatality rate. CONCLUSIONS: the higher rates of COVID-19 in Metropolitan Lima is attributable, among others, to the increased PM(2.5) exposure in the previous years after adjusting for age, sex and number of food markets. Reduction of air pollution since a long-term perspective, and social distancing are needed to prevent spreads of virus outbreak.