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10.21203/rs.3.rs-25639/v1

http://scihub22266oqcxt.onion/10.21203/rs.3.rs-25639/v1
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32702728!7336521!32702728
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suck abstract from ncbi

pmid32702728      Res+Sq 2020 ; ä (ä): ä
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  • A potential role for AHR in SARS-CoV-2 pathology #MMPMID32702728
  • Giovannoni F; Li Z; Garcia CC; Quintana FJ
  • Res Sq 2020[Apr]; ä (ä): ä PMID32702728show ga
  • Coronavirus infection is associated to life-threatening respiratory failure. The aryl hydrocarbon receptor (AHR) was recently identified as a host factor for Zika and dengue viruses; AHR antagonists decrease viral titers and ameliorate ZIKV-induced pathology in vivo. Here we report that AHR is activated during coronavirus infection, impacting anti-viral immunity and lung basal cells associated to tissue repair. Hence, AHR antagonists are candidate therapeutics for the management of coronavirus-infected patients.
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