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10.1093/ckj/sfaa104 http://scihub22266oqcxt.onion/10.1093/ckj/sfaa104 32699615!7367105!32699615     free     free     free       Clin+Kidney+J 2020 ; 13 (3): 297-306 Nephropedia Template TP {{tp|p=32699615|t=2020. Coronavirus disease 2019 in chronic kidney disease |pdf=|usr=}}{{32699615}} gab.com Text Coronavirus disease 2019 in chronic kidney disease JO: Clin Kidney J http://www.kidney.de/pget.php?&tw=1&pmid=32699615 #FOAvip The clinical spectrum of coronavirus disease 2019 (COVID-19) infection ranges from asymptomatic infection to severe pneumonia with respiratory failure and even death. More severe cases with higher mortality have been reported in older patients and in those with chronic illness such as hypertension, diabetes or cardiovascular diseases. In this regard, patients with chronic kidney disease (CKD) have a higher rate of all-type infections and cardiovascular disease than the general population. A markedly altered immune system and immunosuppressed state may predispose CKD patients to infectious complications. Likewise, they have a state of chronic systemic inflammation that may increase their morbidity and mortality. In this review we discuss the chronic immunologic changes observed in CKD patients, the risk of COVID-19 infections and the clinical implications for and specific COVID-19 therapy in CKD patients. Indeed, the risk for severe COVID-19 is 3-fold higher in CKD than in non-CKD patients; CKD is 12-fold more frequent in intensive care unit than in non-hospitalized COVID-19 patients, and this ratio is higher than for diabetes or cardiovascular disease; and acute COVID-19 mortality is 15-25% for haemodialysis patients even when not developing pneumonia. Twit Text FOAVip Coronavirus disease 2019 in chronic kidney disease ????Clin Kidney J http://www.kidney.de/pget.php?&tw=1&pmid=32699615 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32699615 #FOAvip English Wikipedia <ref>{{Cite pmid|32699615}}</ref> Coronavirus disease 2019 in chronic kidney disease #MMPMID32699615 D'Marco L; Puchades MJ; Romero-Parra M; Gimenez-Civera E; Soler MJ; Ortiz A; Gorriz JL Clin Kidney J 2020[Jun]; 13 (3): 297-306 PMID32699615show ga The clinical spectrum of coronavirus disease 2019 (COVID-19) infection ranges from asymptomatic infection to severe pneumonia with respiratory failure and even death. More severe cases with higher mortality have been reported in older patients and in those with chronic illness such as hypertension, diabetes or cardiovascular diseases. In this regard, patients with chronic kidney disease (CKD) have a higher rate of all-type infections and cardiovascular disease than the general population. A markedly altered immune system and immunosuppressed state may predispose CKD patients to infectious complications. Likewise, they have a state of chronic systemic inflammation that may increase their morbidity and mortality. In this review we discuss the chronic immunologic changes observed in CKD patients, the risk of COVID-19 infections and the clinical implications for and specific COVID-19 therapy in CKD patients. Indeed, the risk for severe COVID-19 is 3-fold higher in CKD than in non-CKD patients; CKD is 12-fold more frequent in intensive care unit than in non-hospitalized COVID-19 patients, and this ratio is higher than for diabetes or cardiovascular disease; and acute COVID-19 mortality is 15-25% for haemodialysis patients even when not developing pneumonia. äCoronavirus disease 2019 in chronic kidney disease (epmc).pdf DeepDyve Pubget Overpricing