Abbas AM; Ahmed L; Salem AS; Elsamman SH; Refai A; Fathy SK; Ahmed OA; Shalotut AS; AbdelWahab RA
Am J Reprod Immunol 2020[Nov]; 84 (5): e13310 PMID32698238show ga
The emergence of coronavirus disease 2019 (COVID-19) as a pandemic threatens the entire world resulting in severe consequences for people's health. Pregnant patients with COVID-19 had immune dysregulation that could result in abnormal pregnancy outcomes such as hydatidiform mole (HM), recurrent pregnancy loss, and early-onset preeclampsia. In this article, we tried to summarize the possible association between COVID-19 and the HM's development by reviewing the role of NOD-Like Receptor (NLR) Family Pyrin Domain Containing 7 (NLRP7), cytokines, zinc, and leukocytes in the pathogenesis of HM.
|Adaptor Proteins, Signal Transducing/metabolism[MESH]