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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Cell 2020 ; 182 (4): 794-795 Nephropedia Template TP
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Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear #MMPMID32697970
Grubaugh ND; Hanage WP; Rasmussen AL
Cell 2020[Aug]; 182 (4): 794-795 PMID32697970show ga
In this issue of Cell, Korber et al. found that a SARS-CoV-2 variant in the spike protein D614G rapidly became dominant around the world. Although clinical and in vitro data suggest that D614G changes the virus phenotype, the impact of the mutation on transmission, disease, and vaccine and therapeutic development are largely unknown.