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Vertical transmission of SARS CoV-2: a systematic review #MMPMID32693656
Deniz M; Tezer H
J Matern Fetal Neonatal Med 2022[Jul]; 35 (14): 2655-2662 PMID32693656show ga
OBJECTIVE: The aim of this study is to review the current evidence on the vertical transmission of SARS CoV-2. METHODS: Combination of the following keywords; COVID-19, SARS CoV-2, placenta, vertical transmission, intrauterine infection, breast milk were searched in databases. RESULTS: In the 50 studies included, 17 newborns testing positive for SARS CoV-2 by RT-PCR were reported. In three neonates, SARS-CoV-2 IgG and IgM levels were elevated. Eight placental tissues testing positive for the virus were reported. Three positive RT-PCR results of test of breast milk have been reported recently. One amniotic fluid testing positive was reported. CONCLUSION: Possible vertical transmission of SARS CoV-2 has been observed in some studies currently. More RT-PCR tests on amniotic fluid, placenta, breast milk and cord blood are required.