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10.1080/14767058.2020.1798398

http://scihub22266oqcxt.onion/10.1080/14767058.2020.1798398
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32691641!ä!32691641

suck abstract from ncbi


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pmid32691641      J+Matern+Fetal+Neonatal+Med 2020 ; 33 (22): 3820-3826
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  • Outcomes of universal SARS-CoV-2 testing program in pregnant women admitted to hospital and the adjuvant role of lung ultrasound in screening: a prospective cohort study #MMPMID32691641
  • Yassa M; Yirmibes C; Cavusoglu G; Eksi H; Dogu C; Usta C; Mutlu M; Birol P; Gulumser C; Tug N
  • J Matern Fetal Neonatal Med 2020[Nov]; 33 (22): 3820-3826 PMID32691641show ga
  • BACKGROUND: The emerging evidence for the asymptomatic carriers of SARS-CoV-2 infection emphasized the critical need for universal screening of pregnant women. OBJECTIVES: This study aimed to present the prevalence of overall and asymptomatic SARS-CoV-2 infection rates in pregnant women admitted to the hospital, and assess the diagnostic accuracy of maternal symptoms and lung ultrasound (LUS) findings in detecting the infection. PATIENTS AND METHODS: This prospective cohort study was conducted at a single tertiary center in Istanbul, Turkey, for a month period starting from 27 April 2020. Women with a confirmed pregnancy regardless of the gestational week admitted to the obstetric unit with any indication were consecutively underwent LUS and PCR testing for SARS-CoV-2. RESULTS: A total of 296 patients were included for the final analysis. The universal screening strategy diagnosed 23 pregnant women (7.77%) with SARS-CoV-2 infection. The rate of symptomatic and asymptomatic patients diagnosed with SARS-CoV-2 was found as 3.72% (n = 11) and 4.05% (n = 12), respectively. Four of nine women who underwent a second testing for SARS-CoV-2 upon abnormal LUS findings were found positive eventually (17.4%, n = 4/23). The asymptomatic pregnant women with LUS score of 1 and those with normal LUS findings were considered as likely to be normal. Symptomatic patients with LUS score of 1 and those with score of 2 or 3 were considered as abnormal. On a secondary diagnostic performance analysis, the positive predictive value and the sensitivity were found as 44% and 47.8% for the triage based on maternal symptoms and, 82.3% and 60.9% for the triage based on LUS, respectively. CONCLUSION: A one-month trial period of universal testing for SARS-CoV-2 infection with RT-PCR in pregnant women who admitted to the hospital showed an overall and asymptomatic infection diagnose rate of 7.77% and 4%, respectively. Using lung ultrasound was found more predictive in detecting the infection than the use of symptomatology solely.
  • |*Betacoronavirus/isolation & purification[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Asymptomatic Infections/*epidemiology[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Laboratory Techniques/*methods[MESH]
  • |Coronavirus Infections/diagnosis/*epidemiology[MESH]
  • |Female[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Lung/*diagnostic imaging[MESH]
  • |Mass Screening/*methods[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/diagnosis/*epidemiology[MESH]
  • |Pregnancy[MESH]
  • |Pregnancy Complications, Infectious/diagnosis/*epidemiology[MESH]
  • |Prevalence[MESH]
  • |Prospective Studies[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]
  • |Turkey/epidemiology[MESH]
  • |Ultrasonography[MESH]


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