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10.1016/j.ijantimicag.2020.106101 http://scihub22266oqcxt.onion/10.1016/j.ijantimicag.2020.106101 32687949!7366996!32687949     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Antimicrob+Agents 2020 ; 56 (3): 106101 Nephropedia Template TP {{tp|p=32687949|t=2020. Chloroquine and hydroxychloroquine in coronavirus disease 2019 (COVID-19) Facts, fiction and the hype: a critical appraisal |pdf=|usr=}}{{32687949}} gab.com Text Chloroquine and hydroxychloroquine in coronavirus disease 2019 (COVID-19) Facts, fiction and the hype: a critical appraisal JO: Int J Antimicrob Agents http://www.kidney.de/pget.php?&tw=1&pmid=32687949 #FOAvip The coronavirus infection (COVID-19) has turned into a global catastrophe and there is an intense search for effective drug therapy. Of all the potential therapies, chloroquine and hydroxychloroquine have been the focus of tremendous public attention. Both drugs have been used in the treatment and prophylaxis of malaria. Long-term use of hydroxychloroquine is the cornerstone in the treatment of several auto-immune disorders. There is convincing evidence that hydroxychloroquine has strong in vitro antiviral activity against SARS-CoV-2. A few small uncontrolled trials and several anecdotal reports have shown conflicting results of such drug therapy in COVID-19. However, the results of preliminary large-scale randomized controlled trials have failed to show any survival benefit of such drug therapy in COVID-19. Despite the lack of such evidence, hydroxychloroquine has been used as a desperate attempt for prophylaxis and treatment of COVID-19. The drug has wide-ranging drug interactions and potential cardiotoxicity. Indiscriminate unsupervised use can expose the public to serious adverse drug effects. Twit Text FOAVip Chloroquine and hydroxychloroquine in coronavirus disease 2019 (COVID-19) Facts, fiction and the hype: a critical appraisal ????Int J Antimicrob Agents http://www.kidney.de/pget.php?&tw=1&pmid=32687949 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32687949 #FOAvip English Wikipedia <ref>{{Cite pmid|32687949}}</ref> Chloroquine and hydroxychloroquine in coronavirus disease 2019 (COVID-19) Facts, fiction and the hype: a critical appraisal #MMPMID32687949 Khuroo MS Int J Antimicrob Agents 2020[Sep]; 56 (3): 106101 PMID32687949show ga The coronavirus infection (COVID-19) has turned into a global catastrophe and there is an intense search for effective drug therapy. Of all the potential therapies, chloroquine and hydroxychloroquine have been the focus of tremendous public attention. Both drugs have been used in the treatment and prophylaxis of malaria. Long-term use of hydroxychloroquine is the cornerstone in the treatment of several auto-immune disorders. There is convincing evidence that hydroxychloroquine has strong in vitro antiviral activity against SARS-CoV-2. A few small uncontrolled trials and several anecdotal reports have shown conflicting results of such drug therapy in COVID-19. However, the results of preliminary large-scale randomized controlled trials have failed to show any survival benefit of such drug therapy in COVID-19. Despite the lack of such evidence, hydroxychloroquine has been used as a desperate attempt for prophylaxis and treatment of COVID-19. The drug has wide-ranging drug interactions and potential cardiotoxicity. Indiscriminate unsupervised use can expose the public to serious adverse drug effects. |Anti-Inflammatory Agents/*administration & dosage/adverse effects[MESH] |Antiviral Agents/*administration & dosage/adverse effects[MESH] |Betacoronavirus/drug effects/growth & development/immunology[MESH] |COVID-19[MESH] |Chloroquine/*administration & dosage/adverse effects[MESH] |Clinical Trials as Topic[MESH] |Coronavirus Infections/*drug therapy/mortality/prevention & control/virology[MESH] |Cytokine Release Syndrome/drug therapy/mortality/*prevention & control/virology[MESH] |Cytokines/antagonists & inhibitors/genetics/immunology[MESH] |Drug Administration Schedule[MESH] |Host-Pathogen Interactions/drug effects/genetics/immunology[MESH] |Humans[MESH] |Hydroxychloroquine/*administration & dosage/adverse effects[MESH] |Immunologic Factors/*administration & dosage/adverse effects[MESH] |Pandemics/prevention & control[MESH] |Pneumonia, Viral/*drug therapy/mortality/prevention & control/virology[MESH] |SARS-CoV-2[MESH] |Survival Analysis[MESH] |Virus Internalization/drug effects[MESH]Chloroquine and hydroxychloroquine in coronavirus disease 2019 (COVID-(epmc).pdf DeepDyve Pubget Overpricing