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10.1111/obr.13095

http://scihub22266oqcxt.onion/10.1111/obr.13095
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32686331!7404429!32686331
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suck abstract from ncbi


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pmid32686331      Obes+Rev 2020 ; 21 (10): e13095
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  • Obesity is a risk factor for developing critical condition in COVID-19 patients: A systematic review and meta-analysis #MMPMID32686331
  • Foldi M; Farkas N; Kiss S; Zadori N; Vancsa S; Szako L; Dembrovszky F; Solymar M; Bartalis E; Szakacs Z; Hartmann P; Par G; Eross B; Molnar Z; Hegyi P; Szentesi A
  • Obes Rev 2020[Oct]; 21 (10): e13095 PMID32686331show ga
  • The disease course of COVID-19 varies from asymptomatic infection to critical condition leading to mortality. Identification of prognostic factors is important for prevention and early treatment. We aimed to examine whether obesity is a risk factor for the critical condition in COVID-19 patients by performing a meta-analysis. The review protocol was registered onto PROSPERO (CRD42020185980). A systematic search was performed in five scientific databases between 1 January and 11 May 2020. After selection, 24 retrospective cohort studies were included in the qualitative and quantitative analyses. We calculated pooled odds ratios (OR) with 95% confidence intervals (CIs) in meta-analysis. Obesity was a significant risk factor for intensive care unit (ICU) admission in a homogenous dataset (OR = 1.21, CI: 1.002-1.46; I2 = 0.0%) as well as for invasive mechanical ventilation (IMV) (OR = 2.05, CI: 1.16-3.64; I2 = 34.86%) in COVID-19. Comparing body mass index (BMI) classes with each other, we found that a higher BMI always carries a higher risk. Obesity may serve as a clinical predictor for adverse outcomes; therefore, the inclusion of BMI in prognostic scores and improvement of guidelines for the intensive care of patients with elevated BMI are highly recommended.
  • |*Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*complications[MESH]
  • |Critical Illness[MESH]
  • |Humans[MESH]
  • |Obesity/*complications[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*complications[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]


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