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Thrombosis and coagulopathy in COVID-19: An illustrated review #MMPMID32685883
Levi M; Hunt BJ
Res Pract Thromb Haemost 2020[Jul]; 4 (5): 744-751 PMID32685883show ga
This illustrated review discusses the haemostatic changes seen in patients with severe coronavirus disease 2019 (COVID-19) infection and their possible causes. We discuss the crosstalk between inflammation and coagulation resulting in high levels of acute-phase proteins, very high levels of D-dimers, and absence of disseminated intravascular coagulation seen in patients with severe COVID-19. There appear to be high rates of venous thromboembolism and also, what has been poorly described before in acute lung injury, a high rate of pulmonary immunothrombosis (thrombosis secondary to inflammation).