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10.1161/STROKEAHA.120.030995

http://scihub22266oqcxt.onion/10.1161/STROKEAHA.120.030995
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32684145!7386677!32684145
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suck abstract from ncbi


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pmid32684145      Stroke 2020 ; 51 (9): e219-e222
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  • Acute Cerebrovascular Events in Hospitalized COVID-19 Patients #MMPMID32684145
  • Rothstein A; Oldridge O; Schwennesen H; Do D; Cucchiara BL
  • Stroke 2020[Sep]; 51 (9): e219-e222 PMID32684145show ga
  • BACKGROUND AND PURPOSE: Initial reports suggest a significant risk of thrombotic events, including stroke, in patients hospitalized with coronavirus disease 2019 (COVID-19). However, there is little systematic data on stroke incidence and mechanisms, particularly in racially diverse populations in the United States. METHODS: We performed a retrospective, observational study of stroke incidence and mechanisms in all patients with COVID-19 hospitalized from March 15 to May 3, 2020, at 3 Philadelphia hospitals. RESULTS: We identified 844 hospitalized patients with COVID-19 (mean age 59 years, 52% female, 68% Black); 20 (2.4%) had confirmed ischemic stroke; and 8 (0.9%) had intracranial hemorrhage. Of the ischemic stroke patients, mean age was 64 years, with only one patient (5%) under age 50, and 80% were Black. Conventional vascular risk factors were common, with 95% of patients having a history of hypertension and 60% a history of diabetes mellitus. Median time from onset of COVID symptoms to stroke diagnosis was 21 days. Stroke mechanism was cardioembolism in 40%, small vessel disease in 5%, other determined mechanism in 20%, and cryptogenic in 35%. Of the 11 patients with complete vascular imaging, 3 (27%) had large vessel occlusion. Newly positive antiphospholipid antibodies were present in >75% of tested patients. Of the patients with intracranial hemorrhage, 5/8 (63%) were lobar intraparenchymal hemorrhages, and 3/8 (38%) were subarachnoid hemorrhage; 4/8 (50%) were on extracorporeal membrane oxygenation. CONCLUSIONS: We found a low risk of acute cerebrovascular events in patients hospitalized with COVID-19. Most patients with ischemic stroke had conventional vascular risk factors, and traditional stroke mechanisms were common.
  • |Aged[MESH]
  • |Black People[MESH]
  • |Brain Ischemia/complications/epidemiology[MESH]
  • |COVID-19[MESH]
  • |Cerebrovascular Disorders/*complications/*epidemiology[MESH]
  • |Coronavirus Infections/*complications/*epidemiology[MESH]
  • |Diabetes Complications/epidemiology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Hypertension/complications[MESH]
  • |Incidence[MESH]
  • |Inpatients[MESH]
  • |Intracranial Hemorrhages/complications/epidemiology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Philadelphia/epidemiology[MESH]
  • |Pneumonia, Viral/*complications/*epidemiology[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]
  • |Stroke/complications/epidemiology[MESH]


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