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10.1177/1073858420941476 http://scihub22266oqcxt.onion/10.1177/1073858420941476 32684080!ä!32684080 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Neuroscientist 2020 ; 26 (5-6): 402-414 Nephropedia Template TP {{tp|p=32684080|t=2020. COVID-19, Mast Cells, Cytokine Storm, Psychological Stress, and Neuroinflammation |pdf=|usr=}}{{32684080}} gab.com Text COVID-19, Mast Cells, Cytokine Storm, Psychological Stress, and Neuroinflammation JO: Neuroscientist http://www.kidney.de/pget.php?&tw=1&pmid=32684080 #FOAvip Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new pandemic infectious disease that originated in China. COVID-19 is a global public health emergency of international concern. COVID-19 causes mild to severe illness with high morbidity and mortality, especially in preexisting risk groups. Therapeutic options are now limited to COVID-19. The hallmark of COVID-19 pathogenesis is the cytokine storm with elevated levels of interleukin-6 (IL-6), IL-1beta, tumor necrosis factor-alpha (TNF-alpha), chemokine (C-C-motif) ligand 2 (CCL2), and granulocyte-macrophage colony-stimulating factor (GM-CSF). COVID-19 can cause severe pneumonia, and neurological disorders, including stroke, the damage to the neurovascular unit, blood-brain barrier disruption, high intracranial proinflammatory cytokines, and endothelial cell damage in the brain. Mast cells are innate immune cells and also implicated in adaptive immune response, systemic inflammatory diseases, neuroinflammatory diseases, traumatic brain injury and stroke, and stress disorders. SARS-CoV-2 can activate monocytes/macrophages, dendritic cells, T cells, mast cells, neutrophils, and induce cytokine storm in the lung. COVID-19 can activate mast cells, neurons, glial cells, and endothelial cells. SARS-CoV-2 infection can cause psychological stress and neuroinflammation. In conclusion, COVID-19 can induce mast cell activation, psychological stress, cytokine storm, and neuroinflammation. Twit Text FOAVip COVID-19, Mast Cells, Cytokine Storm, Psychological Stress, and Neuroinflammation ????Neuroscientist http://www.kidney.de/pget.php?&tw=1&pmid=32684080 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32684080 #FOAvip English Wikipedia <ref>{{Cite pmid|32684080}}</ref> COVID-19, Mast Cells, Cytokine Storm, Psychological Stress, and Neuroinflammation #MMPMID32684080 Kempuraj D; Selvakumar GP; Ahmed ME; Raikwar SP; Thangavel R; Khan A; Zaheer SA; Iyer SS; Burton C; James D; Zaheer A Neuroscientist 2020[Oct]; 26 (5-6): 402-414 PMID32684080show ga Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new pandemic infectious disease that originated in China. COVID-19 is a global public health emergency of international concern. COVID-19 causes mild to severe illness with high morbidity and mortality, especially in preexisting risk groups. Therapeutic options are now limited to COVID-19. The hallmark of COVID-19 pathogenesis is the cytokine storm with elevated levels of interleukin-6 (IL-6), IL-1beta, tumor necrosis factor-alpha (TNF-alpha), chemokine (C-C-motif) ligand 2 (CCL2), and granulocyte-macrophage colony-stimulating factor (GM-CSF). COVID-19 can cause severe pneumonia, and neurological disorders, including stroke, the damage to the neurovascular unit, blood-brain barrier disruption, high intracranial proinflammatory cytokines, and endothelial cell damage in the brain. Mast cells are innate immune cells and also implicated in adaptive immune response, systemic inflammatory diseases, neuroinflammatory diseases, traumatic brain injury and stroke, and stress disorders. SARS-CoV-2 can activate monocytes/macrophages, dendritic cells, T cells, mast cells, neutrophils, and induce cytokine storm in the lung. COVID-19 can activate mast cells, neurons, glial cells, and endothelial cells. SARS-CoV-2 infection can cause psychological stress and neuroinflammation. In conclusion, COVID-19 can induce mast cell activation, psychological stress, cytokine storm, and neuroinflammation. |Betacoronavirus/*immunology[MESH] |COVID-19[MESH] |Coronavirus Infections/complications/*immunology/*physiopathology[MESH] |Cytokines/*immunology[MESH] |Humans[MESH] |Mast Cells/*immunology/virology[MESH] |Nervous System Diseases/complications/*immunology[MESH] |Pandemics[MESH] |Pneumonia, Viral/complications/*immunology/*physiopathology[MESH] |SARS-CoV-2[MESH]COVID-19, Mast Cells, Cytokine Storm, Psychological Stress, and Neuro(epmc).pdf DeepDyve Pubget Overpricing