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10.1111/cen.14288

http://scihub22266oqcxt.onion/10.1111/cen.14288
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32683745!7404426!32683745
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suck abstract from ncbi


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pmid32683745      Clin+Endocrinol+(Oxf) 2020 ; 93 (4): 390-393
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  • COVID-19 and diabetes: Insulin requirements parallel illness severity in critically unwell patients #MMPMID32683745
  • Wu L; Girgis CM; Cheung NW
  • Clin Endocrinol (Oxf) 2020[Oct]; 93 (4): 390-393 PMID32683745show ga
  • OBJECTIVE: In the light of increased adverse outcomes for people with diabetes affected by COVID-19, we have described the clinical course of a cohort of critically ill patients with COVID-19 and diabetes. METHODS: We retrospectively analysed characteristics, glucometrics and inflammatory markers of patients with diabetes mellitus admitted to intensive care unit (ICU) with COVID-19. RESULTS: Eight patients with diabetes were admitted to ICU with COVID-19. All had type 2 diabetes, with three being newly diagnosed that admission. Mean HbA1c was 9.2%. Glucometric analysis indicated that extremely high insulin doses were required during peak inflammatory response to maintain glycaemic control with a mean peak insulin requirement of 201 units per day (2.2 units/kg/day). CONCLUSIONS: Critically unwell patients with diabetes mellitus and COVID-19 had high insulin requirements and poorer time in target range at the time of peak inflammatory response, and this improved as their illness resolved.
  • |*Critical Illness[MESH]
  • |*SARS-CoV-2[MESH]
  • |Adult[MESH]
  • |COVID-19/*complications[MESH]
  • |Cohort Studies[MESH]
  • |Diabetes Mellitus, Type 2/*complications/drug therapy/pathology[MESH]
  • |Female[MESH]
  • |Glycated Hemoglobin/analysis[MESH]
  • |Humans[MESH]
  • |Insulin/*administration & dosage[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Retrospective Studies[MESH]


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