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10.1016/j.diabres.2020.108331

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suck abstract from ncbi


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pmid32682810      Diabetes+Res+Clin+Pract 2020 ; 166 (ä): 108331
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  • Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity #MMPMID32682810
  • Halvatsiotis P; Kotanidou A; Tzannis K; Jahaj E; Magira E; Theodorakopoulou M; Konstandopoulou G; Gkeka E; Pourzitaki C; Kapravelos N; Papoti S; Sileli M; Gogos C; Velissaris D; Markou N; Stefanatou E; Vlachogianni G; Aimoniotou E; Komnos A; Zafeiridis T; Koulouvaris P; Armaganidis A; Bamias A; Dimopoulos G
  • Diabetes Res Clin Pract 2020[Aug]; 166 (ä): 108331 PMID32682810show ga
  • AIMS: The aim of the study was to investigate the association between type-2 diabetes mellitus, other underlying diseases and obesity with the outcomes of critically ill Covid-19 patients in Greece. METHODS: In this retrospective observational multi-centre study, data and outcomes of 90 RNA 2109-nCoV confirmed critically ill patients from 8 hospitals throughout Greece, were analysed. All reported information stand through April 13th 2020. RESULTS: The median age of the patients was 65.5 (IQR 56-73), majority were male (80%) and obesity was present in 34.4% of patients most prevalent to younger than 55 years. Hypertension was the prevailing comorbidity (50%), followed by cardiovascular diseases (21.1%) and type-2 diabetes (18.9%). At admission, common symptoms duration had a median of 8 (IQR 5-11) days. A 13.3% of the patients were discharged, 53.4% were still in the ICUs and 28.9% deceased who were hospitalised for fewer days than the survivors [6 (IQR 3-9) vs. 9 (IQR 7-14.5) respectively]. Aging was not a risk factor but diabetes deteriorates the outcomes. Obesity poses a suggestive burden as it was more notable in deceased versus survivors. CONCLUSIONS: Type 2 diabetes and obesity may have contributed to disease severity and mortality in COVID-19 critically ill patients in Greece.
  • |Aged[MESH]
  • |Betacoronavirus/*isolation & purification[MESH]
  • |COVID-19[MESH]
  • |Comorbidity[MESH]
  • |Coronavirus Infections/complications/epidemiology/*mortality/virology[MESH]
  • |Critical Illness/*mortality[MESH]
  • |Diabetes Mellitus/*mortality/physiopathology/virology[MESH]
  • |Female[MESH]
  • |Greece/epidemiology[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Obesity/*mortality/physiopathology/virology[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/complications/epidemiology/*mortality/virology[MESH]
  • |Prognosis[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]


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