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10.3906/sag-2006-164

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32682358!7775688!32682358
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suck abstract from ncbi


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pmid32682358      Turk+J+Med+Sci 2020 ; 50 (8): 1801-1809
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  • COVID-19 experience of the major pandemic response center in the capital: results of the pandemic s first month in Turkey #MMPMID32682358
  • Guner R; Hasanoglu I; Kayaaslan B; Aypak A; Kaya Kalem A; Eser F; Ozdemir B; Saricaoglu EM; Ayhan M; Aybar Bilir Y; Ozkocak Turan I; Erdem D; Mutlu NM; Buzgan T; Dinc B; Akinci E
  • Turk J Med Sci 2020[Dec]; 50 (8): 1801-1809 PMID32682358show ga
  • BACKGROUND/AIM: The aim of this study is to evaluate the epidemiological and clinical characteristics and parameters that determined the clinical course and prognosis of the COVID-19 patients admitted to Ankara City Hospital during the first month of the pandemic in Turkey. MATERIALS AND METHODS: SARS-CoV-2 PCR positive patients who were hospitalized between March 10 and April 10, 2020 were included. RESULTS: Among 222 patients, mean age was higher in severe acute respiratory illness (SARI)/critical disease group (P < 0.001). Median time from illness onset to admission and presence of comorbidity, especially coronary artery disease and chronic obstructive pulmonary disease, were significantly higher in the SARI/critical disease group (P < 0.05). Cough and fever were the most common symptoms, while anosmia and loss of taste were observed in 8.6% and 7.7% patients, respectively. The mortality rate was 5.4%. A high neutrophil/lymphocyte ratio; low lymphocyte, monocyte, and platelet count; elevated liver enzymes; low GFR; and high levels of muscle enzymes, ferritin, and IL-6 on admission were found to be associated with SARI/critical disease (P < 0.05). Bilateral ground-glass opacity and patchy infiltration were more frequently seen in the SARI/critical disease group (P < 0.001). Patients older than 65 years had an 8-fold increased risk for development of SARI/critical disease. CONCLUSION: This cohort study regarding COVID-19 cases in Turkey reveals that older age, presence of comorbidity, bilateral infiltration on CT, high neutrophil/lymphocyte ratio, low monocyte and platelet count, elevated liver enzymes, low GFR, high levels of muscle enzymes, and high levels of ferritin and IL-6 on admission are predictors of SARI and severe disease.
  • |*COVID-19/blood/epidemiology/physiopathology/therapy[MESH]
  • |*Symptom Assessment/methods/statistics & numerical data[MESH]
  • |Age Factors[MESH]
  • |Aged[MESH]
  • |Biomarkers/*blood[MESH]
  • |COVID-19 Nucleic Acid Testing/methods/statistics & numerical data[MESH]
  • |Clinical Deterioration[MESH]
  • |Comorbidity[MESH]
  • |Female[MESH]
  • |Hospitalization/*statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Mortality[MESH]
  • |Prognosis[MESH]
  • |Risk Factors[MESH]


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