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10.1038/s41598-020-68782-w

http://scihub22266oqcxt.onion/10.1038/s41598-020-68782-w
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32681141!7368008!32681141
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suck abstract from ncbi


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pmid32681141      Sci+Rep 2020 ; 10 (1): 11887
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  • Recurrence of positive SARS-CoV-2 viral RNA in recovered COVID-19 patients during medical isolation observation #MMPMID32681141
  • Yuan B; Liu HQ; Yang ZR; Chen YX; Liu ZY; Zhang K; Wang C; Li WX; An YW; Wang JC; Song S
  • Sci Rep 2020[Jul]; 10 (1): 11887 PMID32681141show ga
  • Recently, the recurrence of positive SARS-CoV-2 viral RNA in recovered COVID-19 patients is receiving more attention. Herein we report a cohort study on the follow-up of 182 recovered patients under medical isolation observation. Twenty (10.99%) patients out of the 182 were detected to be SARS-CoV-2 RNA positive (re-positives), although none showed any clinical symptomatic recurrence, indicating that COVID-19 responds well to treatment. Patients aged under 18 years had higher re-positive rates than average, and none of the severely ill patients re-tested positive. There were no significant differences in sex between re-positives and non-re-positives. Notably, most of the re-positives turned negative in the following tests, and all of them carried antibodies against SARS-CoV-2. This indicates that they might not be infectious, although it is still important to perform regular SARS-CoV-2 RNA testing and follow-up for assessment of infectivity. The findings of this study provide information for improving the management of recovered patients, and for differentiating the follow-up of recovered patients with different risk levels.
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Antibodies, Viral/blood[MESH]
  • |Betacoronavirus/*genetics/immunology/isolation & purification[MESH]
  • |COVID-19[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Cohort Studies[MESH]
  • |Coronavirus Infections/genetics/*pathology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/genetics/*pathology[MESH]
  • |RNA, Viral/*metabolism[MESH]
  • |Recurrence[MESH]
  • |Risk[MESH]
  • |SARS-CoV-2[MESH]
  • |Severity of Illness Index[MESH]


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