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10.1055/s-0040-1714369 http://scihub22266oqcxt.onion/10.1055/s-0040-1714369 32679593!7724576!32679593     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Thromb+Haemost 2020 ; 120 (11): 1524-1535 Nephropedia Template TP {{tp|p=32679593|t=2020. Prevalence and Impact of Coagulation Dysfunction in COVID-19 in China: A Meta-Analysis |pdf=|usr=}}{{32679593}} gab.com Text Prevalence and Impact of Coagulation Dysfunction in COVID-19 in China: A Meta-Analysis JO: Thromb Haemost http://www.kidney.de/pget.php?&tw=1&pmid=32679593 #FOAvip BACKGROUND: The aim of this meta-analysis is to assess the prevalence of coagulation dysfunction in Chinese COVID-19 patients and to determine the association of coagulopathy with the severity and prognosis of COVID-19. METHODS: A meta-analysis of the prevalence of different abnormal coagulation indicators in COVID-19 patients in China was performed. The difference of coagulation indicators and the incidence of DIC were compared between severe cases and nonsevere cases as well as nonsurvivors and survivors, respectively. RESULTS: A total of 22 Chinese studies involving 4,889 confirmed COVID-19 inpatients were included. The average D-dimer value of COVID-19 patients is 0.67 microg/mL (95% confidence interval [CI]: 0.56-0.78), and 29.3% (95% CI: 20.1-38.5%) of patients showed elevated D-dimer values. Severe patients had significantly higher D-dimer levels and prolonged prothrombin time (PT) compared with nonsevere patients. Nonsurvivors had significantly higher D-dimer levels, prolonged PT, and decreased platelet count compared with survivors. In total, 6.2% (95% CI: 2.6-9.9%) COVID-19 patients were complicated by disseminated intravascular coagulation (DIC), in which the log risk ratio in nonsurvivors was 3.267 (95% CI: 2.191-4.342, Z = 5.95, p < 0.05) compared with that in survivors. CONCLUSION: The prevalence of coagulopathy in Chinese COVID-19 inpatients is high, and both the abnormal coagulation indicators and DIC are closely associated with the severity and poor prognosis of these COVID-19 patients. Therefore, attention should be paid to coagulation dysfunction in COVID-19 patients. Closely monitoring of coagulation indicators and application of appropriate anticoagulation may improve the prognosis of COVID-19 inpatients in China. Twit Text FOAVip Prevalence and Impact of Coagulation Dysfunction in COVID-19 in China: A Meta-Analysis ????Thromb Haemost http://www.kidney.de/pget.php?&tw=1&pmid=32679593 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32679593 #FOAvip English Wikipedia <ref>{{Cite pmid|32679593}}</ref> Prevalence and Impact of Coagulation Dysfunction in COVID-19 in China: A Meta-Analysis #MMPMID32679593 Jin S; Jin Y; Xu B; Hong J; Yang X Thromb Haemost 2020[Nov]; 120 (11): 1524-1535 PMID32679593show ga BACKGROUND: The aim of this meta-analysis is to assess the prevalence of coagulation dysfunction in Chinese COVID-19 patients and to determine the association of coagulopathy with the severity and prognosis of COVID-19. METHODS: A meta-analysis of the prevalence of different abnormal coagulation indicators in COVID-19 patients in China was performed. The difference of coagulation indicators and the incidence of DIC were compared between severe cases and nonsevere cases as well as nonsurvivors and survivors, respectively. RESULTS: A total of 22 Chinese studies involving 4,889 confirmed COVID-19 inpatients were included. The average D-dimer value of COVID-19 patients is 0.67 microg/mL (95% confidence interval [CI]: 0.56-0.78), and 29.3% (95% CI: 20.1-38.5%) of patients showed elevated D-dimer values. Severe patients had significantly higher D-dimer levels and prolonged prothrombin time (PT) compared with nonsevere patients. Nonsurvivors had significantly higher D-dimer levels, prolonged PT, and decreased platelet count compared with survivors. In total, 6.2% (95% CI: 2.6-9.9%) COVID-19 patients were complicated by disseminated intravascular coagulation (DIC), in which the log risk ratio in nonsurvivors was 3.267 (95% CI: 2.191-4.342, Z = 5.95, p < 0.05) compared with that in survivors. CONCLUSION: The prevalence of coagulopathy in Chinese COVID-19 inpatients is high, and both the abnormal coagulation indicators and DIC are closely associated with the severity and poor prognosis of these COVID-19 patients. Therefore, attention should be paid to coagulation dysfunction in COVID-19 patients. Closely monitoring of coagulation indicators and application of appropriate anticoagulation may improve the prognosis of COVID-19 inpatients in China. |*Blood Coagulation/drug effects[MESH] |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Anticoagulants/therapeutic use[MESH] |Blood Coagulation Disorders/blood/drug therapy/*epidemiology/mortality[MESH] |COVID-19[MESH] |China/epidemiology[MESH] |Coronavirus Infections/blood/*epidemiology/mortality/therapy[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |Pneumonia, Viral/blood/*epidemiology/mortality/therapy[MESH] |Prevalence[MESH] |Prognosis[MESH] |Risk Assessment[MESH] |Risk Factors[MESH]Prevalence and Impact of Coagulation Dysfunction in COVID-19 in China:(epmc).pdf DeepDyve Pubget Overpricing