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10.1038/s41390-020-1065-5

http://scihub22266oqcxt.onion/10.1038/s41390-020-1065-5
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32679582!ä!32679582

suck abstract from ncbi


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pmid32679582      Pediatr+Res 2021 ; 89 (5): 1101-1108
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  • A literature review of 2019 novel coronavirus (SARS-CoV2) infection in neonates and children #MMPMID32679582
  • Di Nardo M; van Leeuwen G; Loreti A; Barbieri MA; Guner Y; Locatelli F; Ranieri VM
  • Pediatr Res 2021[Apr]; 89 (5): 1101-1108 PMID32679582show ga
  • At the time of writing, there are already millions of documented infections worldwide by the novel coronavirus 2019 (2019-nCoV or severe acute respiratory syndrome coronavirus 2 (SARS-CoV2)), with hundreds of thousands of deaths. The great majority of fatal events have been recorded in adults older than 70 years; of them, a large proportion had comorbidities. Since data regarding the epidemiologic and clinical characteristics in neonates and children developing coronavirus disease 2019 (COVID-19) are scarce and originate mainly from one country (China), we reviewed all the current literature from 1 December 2019 to 7 May 2020 to provide useful information about SARS-CoV2 viral biology, epidemiology, diagnosis, clinical features, treatment, prevention, and hospital organization for clinicians dealing with this selected population. IMPACT: Children usually develop a mild form of COVID-19, rarely requiring high-intensity medical treatment in pediatric intensive care unit. Vertical transmission is unlikely, but not completely excluded. Children with confirmed or suspected COVID-19 must be isolated and healthcare workers should wear appropriate protective equipment. Some clinical features (higher incidence of fever, vomiting and diarrhea, and a longer incubation period) are more common in children than in adults, as well as some radiologic aspects (more patchy shadow opacities on CT scan images than ground-glass opacities). Supportive and symptomatic treatments (oxygen therapy and antibiotics for preventing/treating bacterial coinfections) are recommended in these patients.
  • |*SARS-CoV-2[MESH]
  • |Age Distribution[MESH]
  • |Antiviral Agents/therapeutic use[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |COVID-19 Testing[MESH]
  • |COVID-19/diagnosis/*epidemiology/therapy/transmission[MESH]
  • |Child[MESH]
  • |Cohort Studies[MESH]
  • |Conservative Treatment[MESH]
  • |Coronaviridae/physiology[MESH]
  • |Facility Design and Construction[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Infant, Newborn[MESH]
  • |Lung/diagnostic imaging/virology[MESH]
  • |Oxygen Inhalation Therapy[MESH]
  • |Patient Isolation[MESH]
  • |Renin-Angiotensin System/physiology[MESH]


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