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10.1016/j.lfs.2020.118097 http://scihub22266oqcxt.onion/10.1016/j.lfs.2020.118097 32679148!7361088!32679148     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Life+Sci 2020 ; 257 (ä): 118097 Nephropedia Template TP {{tp|p=32679148|t=2020. The bio-mission of interleukin-6 in the pathogenesis of COVID-19: A brief look at potential therapeutic tactics |pdf=|usr=}}{{32679148}} gab.com Text The bio-mission of interleukin-6 in the pathogenesis of COVID-19: A brief look at potential therapeutic tactics JO: Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=32679148 #FOAvip Interleukin-6 (IL-6), known as an inflammatory cytokine, can be involved in many innate and adaptive immune responses. The role of IL-6 in the pathogenesis of the novel coronavirus disease 2019 (COVID-19) has recently received much more attention due to the spread of the virus and its pandemic potential. Cytokine storm is among the most critical pathological events in patients affected with coronaviruses (CoVs), i.e., severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and COVID-19, causing inflammation-induced lung injury and also occurring as a result of dysregulation of immune responses to the mentioned viruses. IL-6, along with some other inflammatory cytokines, including IL-1 beta (beta), IL-8, and tumor necrosis factor-alpha (TNF-alpha), as well as inflammatory chemokines, can significantly contribute to, fever, lymphopenia, coagulation, lung injury, and multi-organ failure (MOF). Therefore, researchers are to explore novel approaches to treat the disease through targeting of IL-6 and its receptors based on prior experience of other disorders. In this review article, the latest findings on the role of IL-6 in the pathogenesis of COVID-19, as well as therapeutic perspectives, were summarized and discussed. Twit Text FOAVip The bio-mission of interleukin-6 in the pathogenesis of COVID-19: A brief look at potential therapeutic tactics ????Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=32679148 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32679148 #FOAvip English Wikipedia <ref>{{Cite pmid|32679148}}</ref> The bio-mission of interleukin-6 in the pathogenesis of COVID-19: A brief look at potential therapeutic tactics #MMPMID32679148 Abbasifard M; Khorramdelazad H Life Sci 2020[Sep]; 257 (ä): 118097 PMID32679148show ga Interleukin-6 (IL-6), known as an inflammatory cytokine, can be involved in many innate and adaptive immune responses. The role of IL-6 in the pathogenesis of the novel coronavirus disease 2019 (COVID-19) has recently received much more attention due to the spread of the virus and its pandemic potential. Cytokine storm is among the most critical pathological events in patients affected with coronaviruses (CoVs), i.e., severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and COVID-19, causing inflammation-induced lung injury and also occurring as a result of dysregulation of immune responses to the mentioned viruses. IL-6, along with some other inflammatory cytokines, including IL-1 beta (beta), IL-8, and tumor necrosis factor-alpha (TNF-alpha), as well as inflammatory chemokines, can significantly contribute to, fever, lymphopenia, coagulation, lung injury, and multi-organ failure (MOF). Therefore, researchers are to explore novel approaches to treat the disease through targeting of IL-6 and its receptors based on prior experience of other disorders. In this review article, the latest findings on the role of IL-6 in the pathogenesis of COVID-19, as well as therapeutic perspectives, were summarized and discussed. |Betacoronavirus/*immunology/metabolism[MESH] |COVID-19[MESH] |Coronavirus Infections/*immunology/metabolism[MESH] |Cytokines/immunology[MESH] |Humans[MESH] |Inflammation/immunology[MESH] |Interleukin-6/*immunology/metabolism/pharmacology[MESH] |Middle East Respiratory Syndrome Coronavirus/immunology[MESH] |Pandemics[MESH] |Pneumonia, Viral/*immunology/metabolism[MESH] |SARS-CoV-2[MESH]The bio-mission of interleukin-6 in the pathogenesis of COVID-19: A br(epmc).pdf DeepDyve Pubget Overpricing