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10.1093/ageing/afaa167 http://scihub22266oqcxt.onion/10.1093/ageing/afaa167 32678866!7454252!32678866     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32678866&cmd=llinks): Failed to open stream: HTTP request failed! 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Comparing associations between frailty and mortality in hospitalised older adults with or without COVID-19 infection: a retrospective observational study using electronic health records |pdf=|usr=}}{{32678866}} gab.com Text Comparing associations between frailty and mortality in hospitalised older adults with or without COVID-19 infection: a retrospective observational study using electronic health records JO: Age Ageing http://www.kidney.de/pget.php?&tw=1&pmid=32678866 #FOAvip BACKGROUND: The aim of this study was to describe outcomes in hospitalised older people with different levels of frailty and COVID-19 infection. METHODS: We undertook a single-centre, retrospective cohort study examining COVID-19-related mortality using electronic health records, for older people (65 and over) with frailty, hospitalised with or without COVID-19 infection. Baseline covariates included demographics, early warning scores, Charlson Comorbidity Indices and frailty (Clinical Frailty Scale, CFS), linked to COVID-19 status. FINDINGS: We analysed outcomes on 1,071 patients with COVID-19 test results (285 (27%) were positive for COVID-19). The mean age at ED arrival was 79.7 and 49.4% were female. All-cause mortality (by 30 days) rose from 9 (not frail) to 33% (severely frail) in the COVID-negative cohort but was around 60% for all frailty categories in the COVID-positive cohort. In adjusted analyses, the hazard ratio for death in those with COVID-19 compared to those without COVID-19 was 7.3 (95% CI: 3.00, 18.0) with age, comorbidities and illness severity making small additional contributions. INTERPRETATION: In this study, frailty measured using the CFS appeared to make little incremental contribution to the hazard of dying in older people hospitalised with COVID-19 infection; illness severity and comorbidity had a modest association with the overall adjusted hazard of death, whereas confirmed COVID-19 infection dominated, with a sevenfold hazard for death. Twit Text FOAVip Comparing associations between frailty and mortality in hospitalised older adults with or without COVID-19 infection: a retrospective observational study using electronic health records ????Age Ageing http://www.kidney.de/pget.php?&tw=1&pmid=32678866 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32678866 #FOAvip English Wikipedia <ref>{{Cite pmid|32678866}}</ref> Comparing associations between frailty and mortality in hospitalised older adults with or without COVID-19 infection: a retrospective observational study using electronic health records #MMPMID32678866 Owen RK; Conroy SP; Taub N; Jones W; Bryden D; Pareek M; Faull C; Abrams KR; Davis D; Banerjee J Age Ageing 2021[Feb]; 50 (2): 307-316 PMID32678866show ga BACKGROUND: The aim of this study was to describe outcomes in hospitalised older people with different levels of frailty and COVID-19 infection. METHODS: We undertook a single-centre, retrospective cohort study examining COVID-19-related mortality using electronic health records, for older people (65 and over) with frailty, hospitalised with or without COVID-19 infection. Baseline covariates included demographics, early warning scores, Charlson Comorbidity Indices and frailty (Clinical Frailty Scale, CFS), linked to COVID-19 status. FINDINGS: We analysed outcomes on 1,071 patients with COVID-19 test results (285 (27%) were positive for COVID-19). The mean age at ED arrival was 79.7 and 49.4% were female. All-cause mortality (by 30 days) rose from 9 (not frail) to 33% (severely frail) in the COVID-negative cohort but was around 60% for all frailty categories in the COVID-positive cohort. In adjusted analyses, the hazard ratio for death in those with COVID-19 compared to those without COVID-19 was 7.3 (95% CI: 3.00, 18.0) with age, comorbidities and illness severity making small additional contributions. INTERPRETATION: In this study, frailty measured using the CFS appeared to make little incremental contribution to the hazard of dying in older people hospitalised with COVID-19 infection; illness severity and comorbidity had a modest association with the overall adjusted hazard of death, whereas confirmed COVID-19 infection dominated, with a sevenfold hazard for death. |*COVID-19/mortality/therapy[MESH] |*Frailty/diagnosis/epidemiology[MESH] |*Geriatric Assessment/methods/statistics & numerical data[MESH] |*Hospital Mortality[MESH] |Aged[MESH] |Comorbidity[MESH] |Early Warning Score[MESH] |Electronic Health Records/statistics & numerical data[MESH] |Female[MESH] |Frail Elderly/*statistics & numerical data[MESH] |Hospitalization/statistics & numerical data[MESH] |Humans[MESH] |Male[MESH] |Proportional Hazards Models[MESH] |Retrospective Studies[MESH] |SARS-CoV-2/isolation & purification[MESH] |Severity of Illness Index[MESH]Comparing associations between frailty and mortality in hospitalised o(epmc).pdf DeepDyve Pubget Overpricing