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Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Laryngoscope 2020 ; 130 (11): 2526-2531 Nephropedia Template TP
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Clinical and Radiological Evaluations of COVID-19 Patients With Anosmia: Preliminary Report #MMPMID32678494
Lechien JR; Michel J; Radulesco T; Chiesa-Estomba CM; Vaira LA; De Riu G; Sowerby L; Hopkins C; Saussez S
Laryngoscope 2020[Nov]; 130 (11): 2526-2531 PMID32678494show ga
OBJECTIVES/HYPOTHESIS: To investigate clinical and radiological features of olfactory clefts of patients with mild coronavirus disease 2019 (COVID-19). STUDY DESIGN: Prospective non controlled study. METHODS: Sixteen COVID-19 patients were recruited. The epidemiological and clinical data were extracted. Nasal complaints were assessed through the 22-item Sino-Nasal Outcome Test. Patients underwent psychophysical olfactory testing, olfactory cleft examination, and computed tomography (CT) scans. RESULTS: Sixteen anosmic patients were included. The mean Sniffin' Sticks score was 4.6 +/- 1.7. The majority of patients had no endoscopical abnormality, with a mean olfactory cleft endoscopy score of 0.6 +/- 0.9. The olfactory clefts were opacified in three patients on the CT scan. The mean radiological olfactory cleft score was 0.7 +/- 0.8. There were no significant correlations between clinical, radiological, and psychophysical olfactory testing. CONCLUSIONS: The olfactory cleft of anosmic COVID-19 patients is free regarding endoscopic examination and imaging. The anosmia etiology is not related to edema of the olfactory cleft. LEVEL OF EVIDENCE: 4 Laryngoscope, 130:2526-2531, 2020.