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10.1038/s41598-020-68622-x http://scihub22266oqcxt.onion/10.1038/s41598-020-68622-x 32678173!7367350!32678173     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2020 ; 10 (1): 11746 Nephropedia Template TP {{tp|p=32678173|t=2020. VOC fingerprints: metabolomic signatures of biothreat agents with and without antibiotic resistance |pdf=|usr=}}{{32678173}} gab.com Text VOC fingerprints: metabolomic signatures of biothreat agents with and without antibiotic resistance JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=32678173 #FOAvip Category A and B biothreat agents are deemed to be of great concern by the US Centers for Disease Control and Prevention (CDC) and include the bacteria Francisella tularensis, Yersinia pestis, Burkholderia mallei, and Brucella species. Underscored by the impact of the 2020 SARS-CoV-2 outbreak, 2016 Zika pandemic, 2014 Ebola outbreak, 2001 anthrax letter attacks, and 1984 Rajneeshee Salmonella attacks, the threat of future epidemics/pandemics and/or terrorist/criminal use of pathogenic organisms warrants continued exploration and development of both classic and alternative methods of detecting biothreat agents. Volatile organic compounds (VOCs) comprise a large and highly diverse group of carbon-based molecules, generally related by their volatility at ambient temperature. Recently, the diagnostic potential of VOCs has been realized, as correlations between the microbial VOC metabolome and specific bacterial pathogens have been identified. Herein, we describe the use of microbial VOC profiles as fingerprints for the identification of biothreat-relevant microbes, and for differentiating between a kanamycin susceptible and resistant strain. Additionally, we demonstrate microbial VOC profiling using a rapid-throughput VOC metabolomics method we refer to as 'simultaneous multifiber headspace solid-phase microextraction' (simulti-hSPME). Finally, through VOC analysis, we illustrate a rapid non-invasive approach to the diagnosis of BALB/c mice infected with either F. tularensis SCHU S4 or Y. pestis CO92. Twit Text FOAVip VOC fingerprints: metabolomic signatures of biothreat agents with and without antibiotic resistance ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=32678173 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32678173 #FOAvip English Wikipedia <ref>{{Cite pmid|32678173}}</ref> VOC fingerprints: metabolomic signatures of biothreat agents with and without antibiotic resistance #MMPMID32678173 Dailey A; Saha J; Zaidi F; Abdirahman H; Haymond A; Alem F; Hakami R; Couch R Sci Rep 2020[Jul]; 10 (1): 11746 PMID32678173show ga Category A and B biothreat agents are deemed to be of great concern by the US Centers for Disease Control and Prevention (CDC) and include the bacteria Francisella tularensis, Yersinia pestis, Burkholderia mallei, and Brucella species. Underscored by the impact of the 2020 SARS-CoV-2 outbreak, 2016 Zika pandemic, 2014 Ebola outbreak, 2001 anthrax letter attacks, and 1984 Rajneeshee Salmonella attacks, the threat of future epidemics/pandemics and/or terrorist/criminal use of pathogenic organisms warrants continued exploration and development of both classic and alternative methods of detecting biothreat agents. Volatile organic compounds (VOCs) comprise a large and highly diverse group of carbon-based molecules, generally related by their volatility at ambient temperature. Recently, the diagnostic potential of VOCs has been realized, as correlations between the microbial VOC metabolome and specific bacterial pathogens have been identified. Herein, we describe the use of microbial VOC profiles as fingerprints for the identification of biothreat-relevant microbes, and for differentiating between a kanamycin susceptible and resistant strain. Additionally, we demonstrate microbial VOC profiling using a rapid-throughput VOC metabolomics method we refer to as 'simultaneous multifiber headspace solid-phase microextraction' (simulti-hSPME). Finally, through VOC analysis, we illustrate a rapid non-invasive approach to the diagnosis of BALB/c mice infected with either F. tularensis SCHU S4 or Y. pestis CO92. |Animals[MESH] |Betacoronavirus/isolation & purification[MESH] |COVID-19[MESH] |Coronavirus Infections/epidemiology/metabolism/virology[MESH] |Disease Outbreaks[MESH] |Drug Resistance, Microbial/drug effects/genetics[MESH] |Female[MESH] |Francisella tularensis/drug effects/isolation & purification/metabolism[MESH] |Kanamycin/pharmacology[MESH] |Metabolomics/*methods[MESH] |Mice[MESH] |Mice, Inbred BALB C[MESH] |Pandemics[MESH] |Pneumonia, Viral/epidemiology/metabolism/virology[MESH] |SARS-CoV-2[MESH] |Solid Phase Microextraction[MESH] |Tularemia/*metabolism/microbiology/pathology/veterinary[MESH] |Volatile Organic Compounds/analysis/isolation & purification/*metabolism[MESH]VOC fingerprints: metabolomic signatures of biothreat agents with and (epmc).pdf DeepDyve Pubget Overpricing