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10.1016/j.tim.2020.06.005 http://scihub22266oqcxt.onion/10.1016/j.tim.2020.06.005 32674988!7357975!32674988     free     free     free       Trends+Microbiol 2020 ; 28 (11): 934-946 Nephropedia Template TP {{tp|p=32674988|t=2020. Human Organs-on-Chips for Virology |pdf=|usr=}}{{32674988}} gab.com Text Human Organs-on-Chips for Virology JO: Trends Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=32674988 #FOAvip While conventional in vitro culture systems and animal models have been used to study the pathogenesis of viral infections and to facilitate development of vaccines and therapeutics for viral diseases, models that can accurately recapitulate human responses to infection are still lacking. Human organ-on-a-chip (Organ Chip) microfluidic culture devices that recapitulate tissue-tissue interfaces, fluid flows, mechanical cues, and organ-level physiology have been developed to narrow the gap between in vitro experimental models and human pathophysiology. Here, we describe how recent developments in Organ Chips have enabled re-creation of complex pathophysiological features of human viral infections in vitro. Twit Text FOAVip Human Organs-on-Chips for Virology ????Trends Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=32674988 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32674988 #FOAvip English Wikipedia <ref>{{Cite pmid|32674988}}</ref> Human Organs-on-Chips for Virology #MMPMID32674988 Tang H; Abouleila Y; Si L; Ortega-Prieto AM; Mummery CL; Ingber DE; Mashaghi A Trends Microbiol 2020[Nov]; 28 (11): 934-946 PMID32674988show ga While conventional in vitro culture systems and animal models have been used to study the pathogenesis of viral infections and to facilitate development of vaccines and therapeutics for viral diseases, models that can accurately recapitulate human responses to infection are still lacking. Human organ-on-a-chip (Organ Chip) microfluidic culture devices that recapitulate tissue-tissue interfaces, fluid flows, mechanical cues, and organ-level physiology have been developed to narrow the gap between in vitro experimental models and human pathophysiology. Here, we describe how recent developments in Organ Chips have enabled re-creation of complex pathophysiological features of human viral infections in vitro. |*Virus Physiological Phenomena[MESH] |Animals[MESH] |Humans[MESH] |Microfluidics/instrumentation/*methods[MESH] |Organ Culture Techniques/instrumentation/*methods[MESH] |Virology/instrumentation/*methods[MESH] |Virus Diseases/*virology[MESH]Human Organs-on-Chips for Virology (epmc).pdf DeepDyve Pubget Overpricing