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10.1177/2150132720942695

http://scihub22266oqcxt.onion/10.1177/2150132720942695
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32674696!7370565!32674696
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suck abstract from ncbi


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pmid32674696      J+Prim+Care+Community+Health 2020 ; 11 (ä): 2150132720942695
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  • Geographical Profiles of COVID-19 Outbreak in Tokyo: An Analysis of the Primary Care Clinic-Based Point-of-Care Antibody Testing #MMPMID32674696
  • Takita M; Matsumura T; Yamamoto K; Yamashita E; Hosoda K; Hamaki T; Kusumi E
  • J Prim Care Community Health 2020[Jan]; 11 (ä): 2150132720942695 PMID32674696show ga
  • Introduction: The primary care clinic plays a major role in triage for coronavirus disease 2019 (COVID-19), where seroprevalence in the setting of primary care clinic remains less clear. As a point-of-care immunodiagnostic test for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the serosurvey represents an alternative to the polymerase chain reaction (PCR) test to measure the magnitude of COVID-19 outbreak in the communities lacking sufficient diagnostic capability for PCR testing. Methods: We assessed seropositivity for the SARS-CoV-2 IgG between April 21 and May 20, 2020, at 2 primary care clinics in Tokyo, Japan. Results: The overall positive percentage of SARS-CoV-2 IgG was 3.83% (95% confidence interval [CI]: 2.76-5.16) for the entire cohort (n = 1071). The 23 special wards of central Tokyo exhibited a significantly higher prevalence compared with the other areas of Tokyo after classification by residence (P = .02, 4.68% [3.08-6.79] vs 1.83 [0.68-3.95] in central and suburban Tokyo, respectively). In central Tokyo, the southern area showed the highest seroprevalence compared with the other areas (7.92% [3.48-15.01]), corresponding to the cumulative number of confirmed COVID-19 patients by PCR test reported by the Tokyo Metropolitan Government. Conclusion: The seroprevalence surveyed in this study was too low for herd immunity, suggesting the need for robust disease control and prevention. A regional-level approach, rather than state- or prefectural-level, could be of importance in ascertaining detailed profiles of the COVID-19 outbreak.
  • |*Disease Outbreaks[MESH]
  • |*Primary Health Care[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Antibodies, Viral/blood[MESH]
  • |Betacoronavirus/immunology[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Laboratory Techniques[MESH]
  • |Coronavirus Infections/*diagnosis/*epidemiology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immunoglobulin G/blood[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnosis/*epidemiology[MESH]
  • |Point-of-Care Systems[MESH]
  • |Residence Characteristics/*statistics & numerical data[MESH]
  • |SARS-CoV-2[MESH]
  • |Seroepidemiologic Studies[MESH]
  • |Tokyo/epidemiology[MESH]


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