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10.1021/acschemneuro.0c00406 http://scihub22266oqcxt.onion/10.1021/acschemneuro.0c00406 32673476!7467568!32673476     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32673476&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       ACS+Chem+Neurosci 2020 ; 11 (15): 2152-2155 Nephropedia Template TP {{tp|p=32673476|t=2020. Anosmia in COVID-19: A Bumpy Road to Establishing a Cellular Mechanism |pdf=|usr=}}{{32673476}} gab.com Text Anosmia in COVID-19: A Bumpy Road to Establishing a Cellular Mechanism JO: ACS Chem Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=32673476 #FOAvip It has become clear since the pandemic broke out that SARS-CoV-2 virus causes reduction of smell and taste in a significant fraction of COVID-19 patients. The olfactory dysfunction often occurs early in the course of the disease, and sometimes it is the only symptom in otherwise asymptomatic carriers. The cellular mechanisms for these specific olfactory disturbances in COVID-19 are now beginning to be elucidated. Several very recent papers contributed to explaining the key cellular steps occurring in the olfactory epithelium leading to anosmia/hyposmia (collectively known as dysosmia) initiated by SARS-CoV-2 infection. In this Viewpoint, we discuss current progress in research on olfactory dysfunction in COVID-19 and we also propose an updated model of the SARS-CoV-2-induced dysosmia. The emerging central role of sustentacular cells and inflammatory processes in the olfactory epithelium are particularly considered. The proposed model of anosmia in COVID-19 does not answer unequivocally whether the new coronavirus exploits the olfactory route to rapidly or slowly reach the brain in COVID-19 patients. To answer this question, new systematic studies using an infectious virus and appropriate animal models are needed. Twit Text FOAVip Anosmia in COVID-19: A Bumpy Road to Establishing a Cellular Mechanism ????ACS Chem Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=32673476 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32673476 #FOAvip English Wikipedia <ref>{{Cite pmid|32673476}}</ref> Anosmia in COVID-19: A Bumpy Road to Establishing a Cellular Mechanism #MMPMID32673476 Bilinska K; Butowt R ACS Chem Neurosci 2020[Aug]; 11 (15): 2152-2155 PMID32673476show ga It has become clear since the pandemic broke out that SARS-CoV-2 virus causes reduction of smell and taste in a significant fraction of COVID-19 patients. The olfactory dysfunction often occurs early in the course of the disease, and sometimes it is the only symptom in otherwise asymptomatic carriers. The cellular mechanisms for these specific olfactory disturbances in COVID-19 are now beginning to be elucidated. Several very recent papers contributed to explaining the key cellular steps occurring in the olfactory epithelium leading to anosmia/hyposmia (collectively known as dysosmia) initiated by SARS-CoV-2 infection. In this Viewpoint, we discuss current progress in research on olfactory dysfunction in COVID-19 and we also propose an updated model of the SARS-CoV-2-induced dysosmia. The emerging central role of sustentacular cells and inflammatory processes in the olfactory epithelium are particularly considered. The proposed model of anosmia in COVID-19 does not answer unequivocally whether the new coronavirus exploits the olfactory route to rapidly or slowly reach the brain in COVID-19 patients. To answer this question, new systematic studies using an infectious virus and appropriate animal models are needed. |*Betacoronavirus[MESH] |Animals[MESH] |COVID-19[MESH] |Coronavirus Infections/*complications/metabolism[MESH] |Humans[MESH] |Olfaction Disorders/*etiology/metabolism/*virology[MESH] |Olfactory Receptor Neurons/*cytology/metabolism/*virology[MESH] |Pandemics[MESH] |Pneumonia, Viral/*complications/metabolism[MESH] |SARS-CoV-2[MESH]Anosmia in COVID-19: A Bumpy Road to Establishing a Cellular Mechanism(epmc).pdf DeepDyve Pubget Overpricing