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10.1007/s41999-020-00359-2

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32671732!7363499!32671732
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suck abstract from ncbi


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pmid32671732      Eur+Geriatr+Med 2020 ; 11 (5): 829-841
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  • Clinical presentation and outcome across age categories among patients with COVID-19 admitted to a Spanish Emergency Department #MMPMID32671732
  • Martin-Sanchez FJ; Del Toro E; Cardassay E; Valls Carbo A; Cuesta F; Vigara M; Gil P; Lopez Picado AL; Martinez Valero C; Miranda JD; Lopez-Ayala P; Chaparro D; Cozar Lopez G; Del Mar Suarez-Cadenas M; Jerez Fernandez P; Angos B; Diaz Del Arco C; Rodriguez Adrada E; Montalvo Moraleda MT; Espejo Paeres C; Fernandez Alonso C; Elvira C; Chacon A; Garcia Brinon MA; Fernandez Rueda JL; Ortega L; Fernandez Perez C; Gonzalez Armengol JJ; Gonzalez Del Castillo J
  • Eur Geriatr Med 2020[Oct]; 11 (5): 829-841 PMID32671732show ga
  • PURPOSE: To determine the differences by age-dependent categories in the clinical profile, presentation, management, and short-term outcomes of patients with laboratory-confirmed COVID-19 admitted to a Spanish Emergency Department (ED). METHODS: Secondary analysis of COVID-19_URG-HCSC registry. We included all consecutive patients with laboratory-confirmed COVID-19 admitted to the ED of the University Hospital Clinico San Carlos (Madrid, Spain). The population was divided into six age groups. Demographic, baseline and acute clinical data, and in-hospital and 30-day outcomes were collected. RESULTS: 1379 confirmed COVID-19 cases (mean age 62 (SD 18) years old; 53.5% male) were included (18.1% < 45 years; 17.8% 45-54 years; 17.9% 55-64 years; 17.2% 65-74 years; 17.0% 75-84 years; and 11.9% >/= 85 years). A statistically significant association was found between demographic, comorbidity, clinical, radiographic, analytical, and therapeutic variables and short-term results according to age-dependent categories. There were less COVID-specific symptoms and more atypical symptoms among older people. Age was a prognostic factor for hospital admission (aOR = 1.04; 95% CI 1.02-1.05) and in-hospital (aOR = 1.08; 95% CI 1.05-1.10) and 30-day mortality (aOR = 1.07; 95% CI 1.04-1.09), and was associated with not being admitted to intensive care (aOR = 0.95; 95% CI 0.93-0.98). CONCLUSIONS: Older age is associated with less COVID-specific symptoms and more atypical symptoms, and poor short-term outcomes. Age has independent prognostic value and may help in shared decision-making in patients with confirmed COVID-19 infection.
  • |*Coronavirus Infections/diagnosis/epidemiology/mortality/therapy[MESH]
  • |*Pandemics[MESH]
  • |*Pneumonia, Viral/diagnosis/epidemiology/mortality/therapy[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Emergency Service, Hospital[MESH]
  • |Female[MESH]
  • |Hospitalization/*statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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