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10.1128/mSphere.00669-20

http://scihub22266oqcxt.onion/10.1128/mSphere.00669-20
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32669462!7364225!32669462
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suck abstract from ncbi


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pmid32669462      mSphere 2020 ; 5 (4): ä
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  • Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics #MMPMID32669462
  • Evans NG
  • mSphere 2020[Jul]; 5 (4): ä PMID32669462show ga
  • Human infection challenge studies involving the intentional infection of research participants with a disease-causing agent have recently been suggested as a means to speed up the search for a vaccine for the ongoing coronavirus disease 2019 (COVID-19) outbreak. Calls for challenge studies, however, rely on the expected social value of these studies. This value represents more than the simple possibility that a successful study will lead to the rapid development and dissemination of vaccines but also some expectation that this will actually occur. I show how this expectation may not be realistic in the current political moment and offer potential ways to make sure that any challenge trials that arise actually achieve their goals.
  • |Betacoronavirus[MESH]
  • |Biomedical Research/*ethics/*methods[MESH]
  • |COVID-19[MESH]
  • |Clinical Trials as Topic/*ethics[MESH]
  • |Coronavirus Infections/*drug therapy/*prevention & control[MESH]
  • |Ethics, Research[MESH]
  • |Humans[MESH]
  • |Pandemics/*prevention & control[MESH]
  • |Pneumonia, Viral/*drug therapy/*prevention & control[MESH]
  • |SARS-CoV-2[MESH]
  • |Social Values[MESH]


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