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10.2337/dbi19-0023 http://scihub22266oqcxt.onion/10.2337/dbi19-0023 32669390!7458034!32669390     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32669390&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Diabetes 2020 ; 69 (9): 1857-1863 Nephropedia Template TP {{tp|p=32669390|t=2020. Aging, Male Sex, Obesity, and Metabolic Inflammation Create the Perfect Storm for COVID-19 |pdf=|usr=}}{{32669390}} gab.com Text Aging, Male Sex, Obesity, and Metabolic Inflammation Create the Perfect Storm for COVID-19 JO: Diabetes http://www.kidney.de/pget.php?&tw=1&pmid=32669390 #FOAvip Coronavirus disease 2019 (COVID-19) is a novel threat that seems to result from the collusion between a new pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and an existing pandemic of metabolic disease driven by obesity. This Perspective explores the evolving epidemiological, clinical, biological, and molecular evidence to propose an unfolding paradigm in which old age, chronic metabolic disease (such as obesity, type 2 diabetes, and metabolic syndrome), and male biological sex produce a deadly symbiosis of dysregulated immunometabolism and chronic systemic inflammation that intensifies virally induced hyperinflammation associated with SARS-CoV-2 infection. It is intended to inspire new research directions and stimulate funding in this field. Twit Text FOAVip Aging, Male Sex, Obesity, and Metabolic Inflammation Create the Perfect Storm for COVID-19 ????Diabetes http://www.kidney.de/pget.php?&tw=1&pmid=32669390 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32669390 #FOAvip English Wikipedia <ref>{{Cite pmid|32669390}}</ref> Aging, Male Sex, Obesity, and Metabolic Inflammation Create the Perfect Storm for COVID-19 #MMPMID32669390 Mauvais-Jarvis F Diabetes 2020[Sep]; 69 (9): 1857-1863 PMID32669390show ga Coronavirus disease 2019 (COVID-19) is a novel threat that seems to result from the collusion between a new pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and an existing pandemic of metabolic disease driven by obesity. This Perspective explores the evolving epidemiological, clinical, biological, and molecular evidence to propose an unfolding paradigm in which old age, chronic metabolic disease (such as obesity, type 2 diabetes, and metabolic syndrome), and male biological sex produce a deadly symbiosis of dysregulated immunometabolism and chronic systemic inflammation that intensifies virally induced hyperinflammation associated with SARS-CoV-2 infection. It is intended to inspire new research directions and stimulate funding in this field. |Adiposity/immunology[MESH] |Age Factors[MESH] |Aging/*immunology[MESH] |Betacoronavirus[MESH] |Black or African American[MESH] |COVID-19[MESH] |Coronavirus Infections/*immunology[MESH] |Cytokine Release Syndrome/immunology[MESH] |Cytokines/immunology[MESH] |Diabetes Mellitus, Type 2/*immunology[MESH] |Ethnicity[MESH] |Female[MESH] |Hispanic or Latino[MESH] |Humans[MESH] |Inflammation/*immunology[MESH] |Male[MESH] |Metabolic Syndrome/*immunology[MESH] |Obesity/*immunology[MESH] |Pandemics[MESH] |Pneumonia, Viral/*immunology[MESH] |Racism[MESH] |SARS-CoV-2[MESH] |Sex Factors[MESH]Aging, Male Sex, Obesity, and Metabolic Inflammation Create the Perfec(epmc).pdf DeepDyve Pubget Overpricing