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10.1053/j.ajkd.2020.06.009 http://scihub22266oqcxt.onion/10.1053/j.ajkd.2020.06.009 32668317!7354772!32668317     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Kidney+Dis 2020 ; 76 (4): 590-594 Nephropedia Template TP {{tp|p=32668317|t=2020. COVID-19-Related Collapsing Glomerulopathy in a Kidney Transplant Recipient |pdf=|usr=}}{{32668317}} gab.com Text COVID-19-Related Collapsing Glomerulopathy in a Kidney Transplant Recipient JO: Am J Kidney Dis http://www.kidney.de/pget.php?&tw=1&pmid=32668317 #FOAvip We report a case of a kidney transplant recipient who presented with acute kidney injury and nephrotic-range proteinuria in a context of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Kidney biopsy revealed collapsing glomerulopathy. Droplet-based digital polymerase chain reaction did not detect the presence of SARS-CoV-2 RNA in the biopsy fragment, and the virus was barely detectable in plasma at the time of the biopsy. SARS-CoV-2 RNAemia peaked several days later, followed by a seroconversion despite the absence of circulating CD19-positive lymphocytes at admission due to rituximab-based treatment of antibody-mediated rejection 3 months earlier. Genotyping for the 2 risk alleles of the apolipoprotein L1 (APOL1) gene revealed that the donor carried the low-risk G0/G2 genotype. This case illustrates that coronavirus disease 2019 infection may promote a collapsing glomerulopathy in kidney allografts with a low-risk APOL1 genotype in the absence of detectable SARS-CoV-2 RNA in the kidney and that podocyte injury may precede SARS-CoV-2 RNAemia. Twit Text FOAVip COVID-19-Related Collapsing Glomerulopathy in a Kidney Transplant Recipient ????Am J Kidney Dis http://www.kidney.de/pget.php?&tw=1&pmid=32668317 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32668317 #FOAvip English Wikipedia <ref>{{Cite pmid|32668317}}</ref> COVID-19-Related Collapsing Glomerulopathy in a Kidney Transplant Recipient #MMPMID32668317 Lazareth H; Pere H; Binois Y; Chabannes M; Schurder J; Bruneau T; Karras A; Thervet E; Rabant M; Veyer D; Pallet N Am J Kidney Dis 2020[Oct]; 76 (4): 590-594 PMID32668317show ga We report a case of a kidney transplant recipient who presented with acute kidney injury and nephrotic-range proteinuria in a context of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Kidney biopsy revealed collapsing glomerulopathy. Droplet-based digital polymerase chain reaction did not detect the presence of SARS-CoV-2 RNA in the biopsy fragment, and the virus was barely detectable in plasma at the time of the biopsy. SARS-CoV-2 RNAemia peaked several days later, followed by a seroconversion despite the absence of circulating CD19-positive lymphocytes at admission due to rituximab-based treatment of antibody-mediated rejection 3 months earlier. Genotyping for the 2 risk alleles of the apolipoprotein L1 (APOL1) gene revealed that the donor carried the low-risk G0/G2 genotype. This case illustrates that coronavirus disease 2019 infection may promote a collapsing glomerulopathy in kidney allografts with a low-risk APOL1 genotype in the absence of detectable SARS-CoV-2 RNA in the kidney and that podocyte injury may precede SARS-CoV-2 RNAemia. |*Kidney Transplantation[MESH] |*Transplant Recipients[MESH] |Adult[MESH] |Allografts[MESH] |Betacoronavirus[MESH] |Biopsy[MESH] |COVID-19[MESH] |Coronavirus Infections/*epidemiology[MESH] |Glomerulonephritis, Membranous/diagnosis/*etiology[MESH] |Humans[MESH] |Kidney/*pathology[MESH] |Male[MESH] |Pandemics[MESH] |Pneumonia, Viral/*epidemiology[MESH]COVID-19-Related Collapsing Glomerulopathy in a Kidney Transplant Reci(epmc).pdf DeepDyve Pubget Overpricing