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10.1002/jso.26127

http://scihub22266oqcxt.onion/10.1002/jso.26127
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32668015!7405118!32668015
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suck abstract from ncbi


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pmid32668015      J+Surg+Oncol 2020 ; 122 (6): 1027-1030
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  • Mortality of high-risk orthopaedic oncology patients during the COVID-19 pandemic: A prospective cohort study #MMPMID32668015
  • Stevenson JD; Evans S; Morris G; Tillman R; Abudu A; Jeys L; Parry M
  • J Surg Oncol 2020[Nov]; 122 (6): 1027-1030 PMID32668015show ga
  • BACKGROUND AND OBJECTIVES: Should the threshold for orthopaedic oncology surgery during the coronavirus disease-2019 (COVID-19) pandemic be higher, particularly in men aged 70 years and older? This study reports the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during, respiratory complications and 30-day mortality during the COVID-19 pandemic. METHODS: This prospective observational cohort study included 100 consecutive patients. The primary outcome measure was 14-day symptoms and/or SARS-CoV-2 test. The secondary outcome was 30-day postoperative mortality. RESULTS: A total of 100 patients comprising 35 females and 65 males, with a mean age of 52.4 years (range, 16-94 years) included 16 males aged greater than 70 years. The 51% of patients were tested during their admission for SARS-CoV-2; 5% were diagnosed/developed symptoms of SARS-CoV-2 during and until 14 days post-discharge; four were male and one female, mean age 41.2 years (range, 17-75 years), all had primary malignant bone or soft-tissue tumours, four of five had received immunosuppressive therapy pre-operatively. The 30-day mortality was 1% overall and 20% in those with SARS-CoV-2. The pulmonary complication rate was 3% overall. CONCLUSIONS: With appropriate peri-operative measures to prevent viral transmission, major surgery for urgent orthopaedic oncology patients can continue during the COVID-19 pandemic. These results need validating with national data to confirm these conclusions.
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*complications/transmission/virology[MESH]
  • |Female[MESH]
  • |Follow-Up Studies[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Neoplasms/complications/*mortality/virology[MESH]
  • |Orthopedic Procedures/*mortality[MESH]
  • |Osteoporotic Fractures/etiology/*mortality/surgery[MESH]
  • |Prognosis[MESH]
  • |Prospective Studies[MESH]
  • |SARS-CoV-2/*isolation & purification[MESH]
  • |Survival Rate[MESH]


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