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10.1002/ccd.29114 http://scihub22266oqcxt.onion/10.1002/ccd.29114 32667726!7405489!32667726     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Catheter+Cardiovasc+Interv 2021 ; 97 (3): E319-E326 Nephropedia Template TP {{tp|p=32667726|t=2021. Changes in characteristics and management among patients with ST-elevation myocardial infarction due to COVID-19 infection |pdf=|usr=}}{{32667726}} gab.com Text Changes in characteristics and management among patients with ST-elevation myocardial infarction due to COVID-19 infection JO: Catheter Cardiovasc Interv http://www.kidney.de/pget.php?&tw=1&pmid=32667726 #FOAvip OBJECTIVES: To assess changes in characteristics and management among ST-elevation myocardial infarction (STEMI) patients with coronavirus disease (COVID-19) who underwent primary percutaneous coronary intervention. METHODS: Our prospective, monocentric study enrolled all STEMI patients who underwent PPCI during the COVID-19 outbreak (n = 83). This cohort was first compared with a previous cohort of STEMI patients (2008-2017, n = 1,552 patients) and was then dichotomized into a non-COVID-19 group (n = 72) and COVID-19 group (n = 11). RESULTS: In comparison with the pre-outbreak period, patients during the outbreak period were older (59.6 +/- 12.9 vs. 62.6 +/- 12.2, p = .03) with a delayed seek to care (mean delay first symptoms-balloon 3.8 +/- 3 vs. .7.4 +/- 7.7, p < .001) resulting in a two-fold higher in-hospital mortality (non COVID-19 4.3% vs. COVID-19 8.4%, p = .07). Among the 83 STEMI patients admitted during the outbreak period, 11 patients were infected by COVID-19. Higher biological markers of inflammation (C-reactive protein: 28 +/- 39 vs. 98 +/- 97 mg/L, p = .04), of fibrinolysis (D-dimer: 804 +/- 1,500 vs. 3,128 +/- 2,458 mug/L, p = .02), and antiphospholipid antibodies in four cases were observed in the COVID-19 group. In this group, angiographic data also differed: a thrombotic myocardial infarction nonatherosclerotic coronary occlusion (MINOCA) was observed in 11 cases (1.4% vs. 54.5%, p < .001) and associated with higher post-procedure distal embolization (30.6% vs. 72.7%, p = .007). The in hospital mortality was significantly higher in the COVID-19 group (5.6% vs. 27.3%, p = .016). CONCLUSION: The COVID-19 outbreak implies deep changes in the etiopathogenesis and therapeutic management of STEMI patients with COVID-19. The impact on early and long-term outcomes of systemic inflammation and hypercoagulability in this specific population is warranted. Twit Text FOAVip Changes in characteristics and management among patients with ST-elevation myocardial infarction due to COVID-19 infection ????Catheter Cardiovasc Interv http://www.kidney.de/pget.php?&tw=1&pmid=32667726 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32667726 #FOAvip English Wikipedia <ref>{{Cite pmid|32667726}}</ref> Changes in characteristics and management among patients with ST-elevation myocardial infarction due to COVID-19 infection #MMPMID32667726 Popovic B; Varlot J; Metzdorf PA; Jeulin H; Goehringer F; Camenzind E Catheter Cardiovasc Interv 2021[Feb]; 97 (3): E319-E326 PMID32667726show ga OBJECTIVES: To assess changes in characteristics and management among ST-elevation myocardial infarction (STEMI) patients with coronavirus disease (COVID-19) who underwent primary percutaneous coronary intervention. METHODS: Our prospective, monocentric study enrolled all STEMI patients who underwent PPCI during the COVID-19 outbreak (n = 83). This cohort was first compared with a previous cohort of STEMI patients (2008-2017, n = 1,552 patients) and was then dichotomized into a non-COVID-19 group (n = 72) and COVID-19 group (n = 11). RESULTS: In comparison with the pre-outbreak period, patients during the outbreak period were older (59.6 +/- 12.9 vs. 62.6 +/- 12.2, p = .03) with a delayed seek to care (mean delay first symptoms-balloon 3.8 +/- 3 vs. .7.4 +/- 7.7, p < .001) resulting in a two-fold higher in-hospital mortality (non COVID-19 4.3% vs. COVID-19 8.4%, p = .07). Among the 83 STEMI patients admitted during the outbreak period, 11 patients were infected by COVID-19. Higher biological markers of inflammation (C-reactive protein: 28 +/- 39 vs. 98 +/- 97 mg/L, p = .04), of fibrinolysis (D-dimer: 804 +/- 1,500 vs. 3,128 +/- 2,458 mug/L, p = .02), and antiphospholipid antibodies in four cases were observed in the COVID-19 group. In this group, angiographic data also differed: a thrombotic myocardial infarction nonatherosclerotic coronary occlusion (MINOCA) was observed in 11 cases (1.4% vs. 54.5%, p < .001) and associated with higher post-procedure distal embolization (30.6% vs. 72.7%, p = .007). The in hospital mortality was significantly higher in the COVID-19 group (5.6% vs. 27.3%, p = .016). CONCLUSION: The COVID-19 outbreak implies deep changes in the etiopathogenesis and therapeutic management of STEMI patients with COVID-19. The impact on early and long-term outcomes of systemic inflammation and hypercoagulability in this specific population is warranted. |Aged[MESH] |Aged, 80 and over[MESH] |COVID-19/*complications/mortality/therapy[MESH] |Cohort Studies[MESH] |Female[MESH] |France[MESH] |Hospital Mortality[MESH] |Hospitalization[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Percutaneous Coronary Intervention[MESH] |ST Elevation Myocardial Infarction/mortality/*therapy/*virology[MESH]Changes in characteristics and management among patients with ST-eleva(epmc).pdf DeepDyve Pubget Overpricing