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10.1111/tid.13418

http://scihub22266oqcxt.onion/10.1111/tid.13418
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32667716!7404440!32667716
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suck abstract from ncbi


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pmid32667716      Transpl+Infect+Dis 2021 ; 23 (1): e13418
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  • Liver transplant recipients infected with SARS-CoV-2 in the early postoperative period: Lessons from a single center in the epicenter of the pandemic #MMPMID32667716
  • Waisberg DR; Abdala E; Nacif LS; Haddad LB; Ducatti L; Santos VR; Gouveia LN; Lazari CS; Martino RB; Pinheiro RS; Arantes RM; Terrabuio DR; Malbouisson LM; Galvao FH; Andraus W; Carneiro-D'Albuquerque LA
  • Transpl Infect Dis 2021[Feb]; 23 (1): e13418 PMID32667716show ga
  • The impact of coronavirus disease-19 (COVID-19) in liver recipients remains largely unknown. Most data derive from small retrospective series of patients transplanted years ago. We aimed to report a single-center case series of five consecutive patients in the early postoperative period of deceased-donor liver transplantation who developed nosocomial COVID-19. Two patients presented important respiratory discomfort and eventually died. One was 69 years old and had severe coronary disease. She rapidly worsened after COVID-19 diagnosis on 9th postoperative day. The other was 67 years old with non-alcoholic steatohepatitis, who experienced prolonged postoperative course, complicated with cytomegalovirus infection and kidney failure. He was diagnosed on 36th postoperative day and remained on mechanical ventilation for 20 days, ultimately succumbing of secondary bacterial infection. The third, fourth, and fifth patients were diagnosed on 10th, 11th, and 18th postoperative day, respectively, and presented satisfactory clinical evolution. These last two patients were severely immunosuppressed, since one underwent steroid bolus for acute cellular rejection and another also used anti-thymocyte globulin for treating steroid-resistant rejection. Our novel experience highlights that COVID-19 may negatively impact the postoperative course, especially in elder and obese patients with comorbidities, and draws attention to COVID-19 nosocomial spread in the early postoperative period.
  • |*Liver Transplantation[MESH]
  • |*SARS-CoV-2[MESH]
  • |*Transplant Recipients[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19/*complications/*epidemiology/therapy[MESH]
  • |Fatal Outcome[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]


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