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10.1080/10428194.2020.1791854

http://scihub22266oqcxt.onion/10.1080/10428194.2020.1791854
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32667230!ä!32667230

suck abstract from ncbi


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pmid32667230      Leuk+Lymphoma 2020 ; 61 (12): 2900-2904
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  • Consensus minimum hemoglobin level above which patients with myelodysplastic syndromes can safely forgo transfusions #MMPMID32667230
  • Tanasijevic AM; Revette A; Klepin HD; Zeidan A; Townsley D; DiNardo CD; Sebert M; DeZern AE; Stone RM; Magnavita ES; Chen R; Sekeres MA; Abel GA
  • Leuk Lymphoma 2020[Dec]; 61 (12): 2900-2904 PMID32667230show ga
  • The anemia of MDS often results in decreased quality of life, which is invoked to justify red cell transfusions; however, there are sparse data regarding the minimum hemoglobin (Hb) at which it is safe to forgo transfusions for patients with no evidence of end-organ damage. This issue is even more important in the COVID-19 era, where decreases in blood donations have stressed the blood supply. In March 2018, using a modified Delphi method, we convened a panel of 13 expert MDS clinicians for three iterative rounds to discuss a minimum safe Hb for this population. While the panel was unable to reach the pre-set consensus of 75% for a specific Hb threshold, there was 100% consensus that it be no greater than 7.5 g/dL. Our data suggest that, given no end-organ effects of anemia, patients with MDS can safely forgo transfusions with a Hb of 7.5 g/dL or higher.
  • |Anemia/diagnosis/etiology/*therapy[MESH]
  • |Blood Donors[MESH]
  • |Blood Transfusion/*standards[MESH]
  • |COVID-19/epidemiology/prevention & control/transmission[MESH]
  • |Clinical Decision-Making[MESH]
  • |Communicable Disease Control/standards[MESH]
  • |Consensus[MESH]
  • |Delphi Technique[MESH]
  • |Hematology/standards[MESH]
  • |Hemoglobins/*analysis/standards[MESH]
  • |Humans[MESH]
  • |Myelodysplastic Syndromes/blood/complications/*therapy[MESH]
  • |Pandemics/prevention & control[MESH]
  • |Practice Guidelines as Topic/*standards[MESH]
  • |Reference Values[MESH]
  • |SARS-CoV-2/pathogenicity[MESH]


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