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10.1021/acsmedchemlett.0c00254 http://scihub22266oqcxt.onion/10.1021/acsmedchemlett.0c00254 32665808!7269097!32665808     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       ACS+Med+Chem+Lett 2020 ; 11 (7): 1357-1360 Nephropedia Template TP {{tp|p=32665808|t=2020. Exploiting Existing Molecular Scaffolds for Long-Term COVID Treatment |pdf=|usr=}}{{32665808}} gab.com Text Exploiting Existing Molecular Scaffolds for Long-Term COVID Treatment JO: ACS Med Chem Lett http://www.kidney.de/pget.php?&tw=1&pmid=32665808 #FOAvip Discovery and development of COVID-19 prophylactics and treatments remains a global imperative. This perspective provides an overview of important molecular pathways involved in the viral life cycle of SARS-CoV-2, the infectious agent of COVID-19. We highlight past and recent findings in essential coronavirus proteins, including RNA polymerase machinery, proteases, and fusion proteins, that offer opportunities for the design of novel inhibitors of SARS-CoV-2 infection. By discussing the current inventory of viral inhibitors, we identify molecular scaffolds that may be improved by medicinal chemistry efforts for effective therapeutics to treat current and future coronavirus-caused diseases. Twit Text FOAVip Exploiting Existing Molecular Scaffolds for Long-Term COVID Treatment ????ACS Med Chem Lett http://www.kidney.de/pget.php?&tw=1&pmid=32665808 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32665808 #FOAvip English Wikipedia <ref>{{Cite pmid|32665808}}</ref> Exploiting Existing Molecular Scaffolds for Long-Term COVID Treatment #MMPMID32665808 Kumar K; Lupoli TJ ACS Med Chem Lett 2020[Jul]; 11 (7): 1357-1360 PMID32665808show ga Discovery and development of COVID-19 prophylactics and treatments remains a global imperative. This perspective provides an overview of important molecular pathways involved in the viral life cycle of SARS-CoV-2, the infectious agent of COVID-19. We highlight past and recent findings in essential coronavirus proteins, including RNA polymerase machinery, proteases, and fusion proteins, that offer opportunities for the design of novel inhibitors of SARS-CoV-2 infection. By discussing the current inventory of viral inhibitors, we identify molecular scaffolds that may be improved by medicinal chemistry efforts for effective therapeutics to treat current and future coronavirus-caused diseases. äExploiting Existing Molecular Scaffolds for Long-Term COVID Treatment (epmc).pdf DeepDyve Pubget Overpricing