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10.1136/bmjgast-2020-000445 http://scihub22266oqcxt.onion/10.1136/bmjgast-2020-000445 32665398!10577726!32665398     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMJ+Open+Gastroenterol 2020 ; 7 (1): ä Nephropedia Template TP {{tp|p=32665398|t=2020. Liver stiffness by transient elastography accompanies illness severity in COVID-19 |pdf=|usr=}}{{32665398}} gab.com Text Liver stiffness by transient elastography accompanies illness severity in COVID-19 JO: BMJ Open Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=32665398 #FOAvip OBJECTIVE: Severe liver damage is associated with worse outcome in COVID-19. Our aim was to explore the degree of liver damage, liver stiffness (LS) and severity of illness in patients with COVID-19. DESIGN: We investigated 32 patients with COVID-19 admitted to the University Hospital of Innsbruck in a prospective cross-sectional study. We performed laboratory testing, liver and spleen sonography and elastography to measure organ stiffness. RESULTS: 12 patients (38%) showed elevated aminotransferases and gamma-glutamyltransferase levels. LS was positively correlated with elevated aminotransferase levels in patients with COVID-19 compared with those without elevated enzymes. Even mild liver damage raised LS significantly in COVID-19 as it was in patients with gastrointestinal symptoms. Furthermore, higher LS measurements were significantly associated with illness severity like pneumonia, need for mechanical ventilation, and even death. CONCLUSION: Transient elastography is a useful and non-invasive tool to assess onset and severity of acute liver injury in patients with COVID-19 patients. Increased LS seems to be predictive for a more severe and complicated course of disease. Twit Text FOAVip Liver stiffness by transient elastography accompanies illness severity in COVID-19 ????BMJ Open Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=32665398 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32665398 #FOAvip English Wikipedia <ref>{{Cite pmid|32665398}}</ref> Liver stiffness by transient elastography accompanies illness severity in COVID-19 #MMPMID32665398 Effenberger M; Grander C; Fritsche G; Bellmann-Weiler R; Hartig F; Wildner S; Seiwald S; Adolph TE; Zoller H; Weiss G; Tilg H BMJ Open Gastroenterol 2020[Jul]; 7 (1): ä PMID32665398show ga OBJECTIVE: Severe liver damage is associated with worse outcome in COVID-19. Our aim was to explore the degree of liver damage, liver stiffness (LS) and severity of illness in patients with COVID-19. DESIGN: We investigated 32 patients with COVID-19 admitted to the University Hospital of Innsbruck in a prospective cross-sectional study. We performed laboratory testing, liver and spleen sonography and elastography to measure organ stiffness. RESULTS: 12 patients (38%) showed elevated aminotransferases and gamma-glutamyltransferase levels. LS was positively correlated with elevated aminotransferase levels in patients with COVID-19 compared with those without elevated enzymes. Even mild liver damage raised LS significantly in COVID-19 as it was in patients with gastrointestinal symptoms. Furthermore, higher LS measurements were significantly associated with illness severity like pneumonia, need for mechanical ventilation, and even death. CONCLUSION: Transient elastography is a useful and non-invasive tool to assess onset and severity of acute liver injury in patients with COVID-19 patients. Increased LS seems to be predictive for a more severe and complicated course of disease. |Aged[MESH] |Betacoronavirus/*genetics[MESH] |Biopsy[MESH] |COVID-19[MESH] |Coronavirus Infections/*complications/epidemiology/virology[MESH] |Cross-Sectional Studies[MESH] |DNA, Viral/analysis[MESH] |Elasticity Imaging Techniques/*methods[MESH] |Female[MESH] |Humans[MESH] |Liver Diseases/*diagnosis/etiology[MESH] |Liver Function Tests[MESH] |Liver/*diagnostic imaging[MESH] |Male[MESH] |Pandemics[MESH] |Pneumonia, Viral/*complications/epidemiology/virology[MESH] |Prospective Studies[MESH] |Reproducibility of Results[MESH] |SARS-CoV-2[MESH]Liver stiffness by transient elastography accompanies illness severity(epmc).pdf DeepDyve Pubget Overpricing