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10.1136/bmjgast-2020-000437

http://scihub22266oqcxt.onion/10.1136/bmjgast-2020-000437
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32665397!7359194!32665397
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suck abstract from ncbi


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pmid32665397      BMJ+Open+Gastroenterol 2020 ; 7 (1): ä
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  • Correlation between gastrointestinal symptoms and disease severity in patients with COVID-19: a systematic review and meta-analysis #MMPMID32665397
  • Liu J; Cui M; Yang T; Yao P
  • BMJ Open Gastroenterol 2020[Jul]; 7 (1): ä PMID32665397show ga
  • OBJECTIVE: To study the correlation between gastrointestinal (GI) symptoms and disease severity in patients with COVID-19. DESIGN: We searched six databases including three Chinese and three English databases for all the published articles on COVID-19. Studies were screened according to inclusion and exclusion criteria. The relevant data were extracted and all the statistical analyses were performed using Revman5.3. RESULT: In a meta-analysis of 9 studies, comprising 3022 patients, 479 patients (13.7%, 95% CI 0.125 to 0.149) had severe disease and 624 patients (14.7%, 95% CI 0.136 to 0.159) had GI symptoms. Of 624 patients with GI symptoms, 118 patients had severe disease (20.5%, 95% CI 0.133 to 0.276) and of 2397 cases without GI symptoms, 361 patients had severe disease (18.2%, 95% CI 0.129 to 0.235). Comparing disease severity of patients with and without GI symptoms, the results indicated: I(2)=62%, OR=1.21, 95% CI 0.94 to 1.56, p=0.13; there was no statistically significant difference between the two groups. The funnel plot was symmetrical with no publication bias. CONCLUSION: Current results are not sufficient to demonstrate a significant correlation between GI symptoms and disease severity in patients with COVID-19.
  • |*Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*complications/diagnosis/epidemiology[MESH]
  • |Gastrointestinal Diseases/diagnosis/*etiology[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*complications/diagnosis/epidemiology[MESH]
  • |SARS-CoV-2[MESH]


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