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Clinical Features of Fatalities in Patients With COVID-19 #MMPMID32665052
Sun YJ; Feng YJ; Chen J; Li B; Luo ZC; Wang PX
Disaster Med Public Health Prep 2021[Apr]; 15 (2): e9-e11 PMID32665052show ga
OBJECTIVES: The novel coronavirus disease 2019 (COVID-19) pandemic has spread to over 213 countries and territories. We sought to describe the clinical features of fatalities in patients with severe COVID-19. METHODS: We conducted an Internet-based retrospective cohort study through retrieving the clinical information of 100 COVID-19 deaths from nonduplicating incidental reports in Chinese provincial and other governmental websites between January 23 and March 10, 2020. RESULTS: Approximately 6 of 10 COVID-19 deaths were males (64.0%). The average age was 70.7 +/- 13.5 y, and 84% of patients were elderly (over age 60 y). The mean duration from admission to diagnosis was 2.2 +/- 3.8 d (median: 1 d). The mean duration from diagnosis to death was 9.9 +/- 7.0 d (median: 9 d). Approximately 3 of 4 cases (76.0%) were complicated by 1 or more chronic diseases, including hypertension (41.0%), diabetes (29.0%) and coronary heart disease (27.0%), respiratory disorders (23.0%), and cerebrovascular disease (12.0%). Fever (46.0%), cough (33.0%), and shortness of breath (9.0%) were the most common first symptoms. Multiple organ failure (67.9%), circulatory failure (20.2%), and respiratory failure (11.9%) are the top 3 direct causes of death. CONCLUSIONS: COVID-19 deaths are mainly elderly and patients with chronic diseases especially cardiovascular disorders and diabetes. Multiple organ failure is the most common direct cause of death.
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Disaster+Med+Public+Health+Prep 2021 ; 15 (2): e9-e11
