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10.1016/j.jcv.2020.104543

http://scihub22266oqcxt.onion/10.1016/j.jcv.2020.104543
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32663787!7340051!32663787
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suck abstract from ncbi


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pmid32663787      J+Clin+Virol 2020 ; 129 (ä): 104543
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  • Analysis of Covid-19 and non-Covid-19 viruses, including influenza viruses, to determine the influence of intensive preventive measures in Japan #MMPMID32663787
  • Hirotsu Y; Maejima M; Shibusawa M; Amemiya K; Nagakubo Y; Hosaka K; Sueki H; Mochizuki H; Tsutsui T; Kakizaki Y; Miyashita Y; Omata M
  • J Clin Virol 2020[Aug]; 129 (ä): 104543 PMID32663787show ga
  • BACKGROUND: Severe acute respiratory coronavirus 2 (SARS-CoV-2) has spread and caused death worldwide. Preventive measures and infection control are underway, and some areas show signs of convergence. Other viruses in addition to SARS-CoV-2 cause cold-like symptoms and spread in the winter. However, the extent to which SARS-CoV-2, influenza viruses and other causative viruses have prevailed since implementing preventive measures is unclear. OBJECTIVES: We aim to investigate the incidence of causative viruses and pathogens in patients. STUDY DESIGN: We collected 191 nasopharyngeal swabs from patients with cold-like symptoms in Japan. All samples were subjected to multiplex PCR with the FilmArray Respiratory Panel and reverse transcription PCR (RT-PCR) to detect SARS-CoV-2. RESULTS: FilmArray Respiratory Panel analysis detected at least one virus in 32 of 191 patients with cold-like symptoms (21 %). Of these, we frequently identified human rhinoviruses/enteroviruses (5.8 %, n=11), human metapneumovirus (3.7 %, n=7), coronavirus 229E (2.1 %, n=4) and coronavirus OC43 (1.6 %, n=3); while no influenza viruses were detected. RT-PCR analysis detected SARS-CoV-2 (4.2 %, n=8) in patients who were not infected with the aforementioned respiratory viruses. CONCLUSIONS: Co-infection with SARS-CoV-2 and other viruses was not observed. Causative viruses remain prevalent after implementing preventive measures. SARS-CoV-2 differs from influenza viruses in its infectivity.
  • |Alphacoronavirus/isolation & purification[MESH]
  • |COVID-19[MESH]
  • |Coinfection/*epidemiology/virology[MESH]
  • |Communicable Disease Control/*methods[MESH]
  • |Coronavirus Infections/*epidemiology/*prevention & control[MESH]
  • |Disease Transmission, Infectious/*prevention & control[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Japan[MESH]
  • |Metapneumovirus/isolation & purification[MESH]
  • |Multiplex Polymerase Chain Reaction[MESH]
  • |Nasopharynx/virology[MESH]
  • |Orthomyxoviridae/isolation & purification[MESH]
  • |Pandemics/*prevention & control[MESH]
  • |Pneumonia, Viral/*epidemiology/*prevention & control[MESH]
  • |Prospective Studies[MESH]
  • |Respiratory Tract Infections/*epidemiology[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]


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