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10.1016/j.mehy.2020.110084 http://scihub22266oqcxt.onion/10.1016/j.mehy.2020.110084 32663741!7346779!32663741     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Med+Hypotheses 2020 ; 143 (ä): 110084 Nephropedia Template TP {{tp|p=32663741|t=2020. Prospective vaccination of COVID-19 using shRNA-plasmid-LDH nanoconjugate |pdf=|usr=}}{{32663741}} gab.com Text Prospective vaccination of COVID-19 using shRNA-plasmid-LDH nanoconjugate JO: Med Hypotheses http://www.kidney.de/pget.php?&tw=1&pmid=32663741 #FOAvip COVID-19 is the pandemic outbreak that is caused by SARS-CoV-2 virus from December, 2019. Human race do not know the curative measure of this devastating disease. In today's era of nanotechnology, it may use its knowledge to develop molecular vaccine to combat this disease. In this article we are intended to propose a hypothesis on the development of a vaccine that is molecular in nature to work against COVID-19. The nanoconjugate may comprise with the inorganic nanoparticle layered double hydroxide intercalated with shRNA-plasmid that have a sequence targeting towards the viral genome or viral mRNA. This nanoconjugate may be used as a nasal spray to deliver the shRNA-plasmid to the target site. The nanoconjugate will have several advantages such as they are biocompatible, they forms as stable knockdown to the target cells and they are stable in the nasal mucosa. Twit Text FOAVip Prospective vaccination of COVID-19 using shRNA-plasmid-LDH nanoconjugate ????Med Hypotheses http://www.kidney.de/pget.php?&tw=1&pmid=32663741 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32663741 #FOAvip English Wikipedia <ref>{{Cite pmid|32663741}}</ref> Prospective vaccination of COVID-19 using shRNA-plasmid-LDH nanoconjugate #MMPMID32663741 Acharya R Med Hypotheses 2020[Oct]; 143 (ä): 110084 PMID32663741show ga COVID-19 is the pandemic outbreak that is caused by SARS-CoV-2 virus from December, 2019. Human race do not know the curative measure of this devastating disease. In today's era of nanotechnology, it may use its knowledge to develop molecular vaccine to combat this disease. In this article we are intended to propose a hypothesis on the development of a vaccine that is molecular in nature to work against COVID-19. The nanoconjugate may comprise with the inorganic nanoparticle layered double hydroxide intercalated with shRNA-plasmid that have a sequence targeting towards the viral genome or viral mRNA. This nanoconjugate may be used as a nasal spray to deliver the shRNA-plasmid to the target site. The nanoconjugate will have several advantages such as they are biocompatible, they forms as stable knockdown to the target cells and they are stable in the nasal mucosa. |*Betacoronavirus/genetics/immunology[MESH] |COVID-19[MESH] |COVID-19 Vaccines[MESH] |Coronavirus Infections/genetics/immunology/*prevention & control/virology[MESH] |Humans[MESH] |Models, Biological[MESH] |Nanoconjugates/chemistry[MESH] |Pandemics/*prevention & control[MESH] |Plasmids/genetics[MESH] |Pneumonia, Viral/immunology/*prevention & control/virology[MESH] |RNA, Small Interfering/genetics[MESH] |RNA, Viral/genetics[MESH] |SARS-CoV-2[MESH] |Vaccines, Synthetic/chemistry/genetics[MESH]Prospective vaccination of COVID-19 using shRNA-plasmid-LDH nanoconjug(epmc).pdf DeepDyve Pubget Overpricing