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10.1053/j.seminoncol.2020.06.002 http://scihub22266oqcxt.onion/10.1053/j.seminoncol.2020.06.002 32660890!7298487!32660890     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Semin+Oncol 2020 ; 47 (5): 335-340 Nephropedia Template TP {{tp|p=32660890|t=2020. Are sex discordant outcomes in COVID-19 related to sex hormones?|pdf=|usr=}}{{32660890}} gab.com Text Are sex discordant outcomes in COVID-19 related to sex hormones JO: Semin Oncol http://www.kidney.de/pget.php?&tw=1&pmid=32660890 #FOAvip COVID-19 has a clear sex disparity in clinical outcome. Globally, infection rates between men and women are similar; however, men are more likely to have more severe disease and are more likely to die. The causes for this disparity are currently under investigation and are most likely multifactorial. Sex hormones play an important role in the immune response with estrogen seen as immune boosting and testosterone as immunosuppressing. Additionally, an important protease involved in viral entry, TMPRSS2, is regulated by androgens. Many observational and prospective studies are ongoing or initiating to further examine the role of sex hormones in SARS-CoV-2 infection and if modulation of them is a realistic treatment option. Twit Text FOAVip Are sex discordant outcomes in COVID-19 related to sex hormones ????Semin Oncol http://www.kidney.de/pget.php?&tw=1&pmid=32660890 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32660890 #FOAvip English Wikipedia <ref>{{Cite pmid|32660890}}</ref> Are sex discordant outcomes in COVID-19 related to sex hormones? #MMPMID32660890 Strope JD; Chau CH; Figg WD Semin Oncol 2020[Oct]; 47 (5): 335-340 PMID32660890show ga COVID-19 has a clear sex disparity in clinical outcome. Globally, infection rates between men and women are similar; however, men are more likely to have more severe disease and are more likely to die. The causes for this disparity are currently under investigation and are most likely multifactorial. Sex hormones play an important role in the immune response with estrogen seen as immune boosting and testosterone as immunosuppressing. Additionally, an important protease involved in viral entry, TMPRSS2, is regulated by androgens. Many observational and prospective studies are ongoing or initiating to further examine the role of sex hormones in SARS-CoV-2 infection and if modulation of them is a realistic treatment option. |*COVID-19 Drug Treatment[MESH] |Androgen Antagonists/therapeutic use[MESH] |COVID-19/epidemiology/metabolism[MESH] |Female[MESH] |Gonadal Steroid Hormones/*metabolism[MESH] |Humans[MESH] |Male[MESH] |Outcome Assessment, Health Care/methods/*statistics & numerical data[MESH] |Pandemics[MESH] |Protease Inhibitors/therapeutic use[MESH] |Serine Endopeptidases/*metabolism[MESH]Are sex discordant outcomes in COVID-19 related to sex hormones?(epmc).pdf DeepDyve Pubget Overpricing