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Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Blood+Purif 2021 ; 50 (1): 102-109 Nephropedia Template TP
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Prevalence, Characteristics, Risk Factors, and Outcomes of Invasively Ventilated COVID-19 Patients with Acute Kidney Injury and Renal Replacement Therapy #MMPMID32659757
Fominskiy EV; Scandroglio AM; Monti G; Calabro MG; Landoni G; Dell'Acqua A; Beretta L; Moizo E; Ravizza A; Monaco F; Campochiaro C; Pieri M; Azzolini ML; Borghi G; Crivellari M; Conte C; Mattioli C; Silvani P; Mucci M; Turi S; Tentori S; Baiardo Redaelli M; Sartorelli M; Angelillo P; Belletti A; Nardelli P; Nisi FG; Valsecchi G; Barberio C; Ciceri F; Serpa Neto A; Dagna L; Bellomo R; Zangrillo A
Blood Purif 2021[]; 50 (1): 102-109 PMID32659757show ga
BACKGROUND: There is no information on acute kidney injury (AKI) and continuous renal replacement therapy (CRRT) among invasively ventilated coronavirus disease 2019 (COVID-19) patients in Western healthcare systems. OBJECTIVE: To study the prevalence, characteristics, risk factors and outcome of AKI and CRRT among invasively ventilated COVID-19 patients. METHODS: Observational study in a tertiary care hospital in Milan, Italy. RESULTS: Among 99 patients, 72 (75.0%) developed AKI and 17 (17.7%) received CRRT. Most of the patients developed stage 1 AKI (33 [45.8%]), while 15 (20.8%) developed stage 2 AKI and 24 (33.4%) a stage 3 AKI. Patients who developed AKI or needed CRRT at latest follow-up were older, and among CRRT treated patients a greater proportion had preexisting CKD. Hospital mortality was 38.9% for AKI and 52.9% for CRRT patients. CONCLUSIONS: Among invasively ventilated COVID-19 patients, AKI is very common and CRRT use is common. Both carry a high risk of in-hospital mortality.