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10.1016/j.clim.2020.108524 http://scihub22266oqcxt.onion/10.1016/j.clim.2020.108524 32659373!7351676!32659373     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Immunol 2020 ; 218 (ä): 108524 Nephropedia Template TP {{tp|p=32659373|t=2020. Long-term infection of SARS-CoV-2 changed the body s immune status |pdf=|usr=}}{{32659373}} gab.com Text Long-term infection of SARS-CoV-2 changed the body s immune status JO: Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32659373 #FOAvip The outbreak of SARS-CoV-2-associated pneumonia, a disease called COVID-19, has caused a pandemic worldwide. To investigate the immune responses after infection of SARS-CoV-2 in non-critical patients may help to better understand the disease progression. We collected 334 confirmed COVID-19 cases including 212 still in hospital with nucleic acid test positive on halfway for SARS-CoV-2 and 122 discharged from hospital, compared specific antibodies, immune cells, and cytokine changes between the hospitalized and discharged patients. The hospitalized patients had a longer illness time compared with discharged patients. Analysis of viral loads explained long-term or persistent infection of SARS-CoV-2, which existed with the median time of 18.5 days of the positive nucleic acid test. Serum analysis showed that the specific anti-N IgG antibody was positive in all detected patients after infection of two weeks. Neutrophils, Monocytes, NK cells, and CD4(+) T cells significantly increased, while total lymphocytes and CD8(+) T cells decreased from non-critical hospitalized patients after longer-term infection. Further analysis of the cytokines showed that IL-6, TNF-alpha, IFN-gamma, IL-2, IL-4, and IL-10 from the hospitalized patients were significantly higher, indicating a potential of the increased CD4(+) T cell differentiation. Twit Text FOAVip Long-term infection of SARS-CoV-2 changed the body s immune status ????Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32659373 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32659373 #FOAvip English Wikipedia <ref>{{Cite pmid|32659373}}</ref> Long-term infection of SARS-CoV-2 changed the body s immune status #MMPMID32659373 Lin L; Luo S; Qin R; Yang M; Wang X; Yang Q; Zhang Y; Wang Q; Zhu R; Fan H; Wang H; Hu Y; Wang L; Hu D Clin Immunol 2020[Sep]; 218 (ä): 108524 PMID32659373show ga The outbreak of SARS-CoV-2-associated pneumonia, a disease called COVID-19, has caused a pandemic worldwide. To investigate the immune responses after infection of SARS-CoV-2 in non-critical patients may help to better understand the disease progression. We collected 334 confirmed COVID-19 cases including 212 still in hospital with nucleic acid test positive on halfway for SARS-CoV-2 and 122 discharged from hospital, compared specific antibodies, immune cells, and cytokine changes between the hospitalized and discharged patients. The hospitalized patients had a longer illness time compared with discharged patients. Analysis of viral loads explained long-term or persistent infection of SARS-CoV-2, which existed with the median time of 18.5 days of the positive nucleic acid test. Serum analysis showed that the specific anti-N IgG antibody was positive in all detected patients after infection of two weeks. Neutrophils, Monocytes, NK cells, and CD4(+) T cells significantly increased, while total lymphocytes and CD8(+) T cells decreased from non-critical hospitalized patients after longer-term infection. Further analysis of the cytokines showed that IL-6, TNF-alpha, IFN-gamma, IL-2, IL-4, and IL-10 from the hospitalized patients were significantly higher, indicating a potential of the increased CD4(+) T cell differentiation. |*Immunity, Innate[MESH] |Aged[MESH] |Antibodies, Viral/blood[MESH] |Betacoronavirus/immunology/*pathogenicity[MESH] |COVID-19[MESH] |Cardiovascular Diseases/epidemiology/*immunology/pathology/virology[MESH] |China/epidemiology[MESH] |Comorbidity[MESH] |Convalescence[MESH] |Coronavirus Infections/epidemiology/*immunology/pathology/virology[MESH] |Cytokines/blood[MESH] |Diabetes Mellitus/epidemiology/*immunology/pathology/virology[MESH] |Female[MESH] |Hospitalization[MESH] |Humans[MESH] |Killer Cells, Natural/immunology/pathology/virology[MESH] |Lung Diseases/epidemiology/*immunology/pathology/virology[MESH] |Lymphocyte Subsets/immunology/pathology/virology[MESH] |Male[MESH] |Middle Aged[MESH] |Monocytes/immunology/pathology/virology[MESH] |Neoplasms/epidemiology/*immunology/pathology/virology[MESH] |Neutrophils/immunology/pathology/virology[MESH] |Pandemics[MESH] |Patient Discharge[MESH] |Pneumonia, Viral/epidemiology/*immunology/pathology/virology[MESH] |SARS-CoV-2[MESH] |Time Factors[MESH]Long-term infection of SARS-CoV-2 changed the body s immune status (epmc).pdf DeepDyve Pubget Overpricing