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10.1111/imr.12897

http://scihub22266oqcxt.onion/10.1111/imr.12897
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32658335!7404857!32658335
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suck abstract from ncbi


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pmid32658335      Immunol+Rev 2020 ; 296 (1): 205-219
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  • The role of host genetics in the immune response to SARS-CoV-2 and COVID-19 susceptibility and severity #MMPMID32658335
  • Ovsyannikova IG; Haralambieva IH; Crooke SN; Poland GA; Kennedy RB
  • Immunol Rev 2020[Jul]; 296 (1): 205-219 PMID32658335show ga
  • This article provides a review of studies evaluating the role of host (and viral) genetics (including variation in HLA genes) in the immune response to coronaviruses, as well as the clinical outcome of coronavirus-mediated disease. The initial sections focus on seasonal coronaviruses, SARS-CoV, and MERS-CoV. We then examine the state of the knowledge regarding genetic polymorphisms and SARS-CoV-2 and COVID-19. The article concludes by discussing research areas with current knowledge gaps and proposes several avenues for future scientific exploration in order to develop new insights into the immunology of SARS-CoV-2.
  • |*Genetic Predisposition to Disease[MESH]
  • |Animals[MESH]
  • |Betacoronavirus/*immunology/pathogenicity[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/epidemiology/genetics/*immunology/virology[MESH]
  • |Disease Resistance/*genetics[MESH]
  • |Host-Pathogen Interactions/*genetics/immunology[MESH]
  • |Humans[MESH]
  • |Middle East Respiratory Syndrome Coronavirus/immunology/pathogenicity[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/epidemiology/genetics/*immunology/virology[MESH]
  • |SARS-CoV-2[MESH]
  • |Severe Acute Respiratory Syndrome/genetics/virology[MESH]


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