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10.1097/BOR.0000000000000728

http://scihub22266oqcxt.onion/10.1097/BOR.0000000000000728
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32657802!ä!32657802

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suck abstract from ncbi


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pmid32657802      Curr+Opin+Rheumatol 2020 ; 32 (5): 458-461
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  • Severe acute respiratory syndrome coronavirus 2, original antigenic sin, and antibody-dependent enhancement: menage a trois #MMPMID32657802
  • Kadkhoda K
  • Curr Opin Rheumatol 2020[Sep]; 32 (5): 458-461 PMID32657802show ga
  • BACKGROUND: Shortly after its emergence in December 2019, the coronavirus disease 2019 (COVID-19) was declared as a pandemic by the World Health Organization. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the seventh member of the Coronaviridae family of viruses that causes disease in humans. THE PROBLEM: Despite the established role of molecular diagnostics, COVID-19 serodiagnosis remains a poorly discovered and enigmatic area. Although there are numerous commercial serological products available globally, there is a severe paucity of high-quality peer-reviewed literature on their true performance characteristics. That being said, publications including in-house developed serological tests started to shed light on the kinetics of the humoral response. SUMMARY: In spite of intense focus of assessing the performance characteristics of the commercially-available kits, the main issue remains rather invisible, that is, lack of solid science behind COVID-19 serology its clinical usefulness thereof. This short review summarizes the key points as to why COVID-19 is not jest ready to fly. PURPOSE OF REVIEW: Despite having been mentioned as a testing option, COVID-19 serology has significant shortcomings that needs discussing. This short review is meant to shed light on one of those aspects.
  • |*Antibody-Dependent Enhancement[MESH]
  • |Antigens, Viral/*immunology[MESH]
  • |Betacoronavirus/*immunology[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*immunology[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*immunology[MESH]
  • |SARS-CoV-2[MESH]


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