Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1080/10826084.2020.1791184 http://scihub22266oqcxt.onion/10.1080/10826084.2020.1791184 32657207!8687452!32657207     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Subst+Use+Misuse 2020 ; 55 (11): 1900-1901 Nephropedia Template TP {{tp|p=32657207|t=2020. Opioid Use Disorder and COVID-19: Biological Plausibility for Worsened Outcomes |pdf=|usr=}}{{32657207}} gab.com Text Opioid Use Disorder and COVID-19: Biological Plausibility for Worsened Outcomes JO: Subst Use Misuse http://www.kidney.de/pget.php?&tw=1&pmid=32657207 #FOAvip Alarms have been raised that COVID-19 may disproportionately affect certain populations with substance use disorders, particularly Opioid Use Disorder (OUD), however warnings have largely focused on social risks such as reduced availability of services. Objectives: This commentary highlights three plausible biological mechanisms for potentially worsened outcomes in patients with OUD who contract COVID-19. Results: Opioid-related respiratory depression may amplify risks of hypoxemia from COVID-19 viral pneumonia. Complex opioid immune modulation may impact host response to COVID-19, though the effect direction and clinical significance are unclear. Drug-drug interactions may affect individuals with OUD who are co-administered medications for OUD and medications for COVID-19, particularly due to cardiac adverse effects. Conclusions/Importance: There are plausible biological mechanisms for potentially worsened outcomes in patients with OUD who contract COVID-19; these mechanisms require further study, and should be considered in individuals with OUD. Twit Text FOAVip Opioid Use Disorder and COVID-19: Biological Plausibility for Worsened Outcomes ????Subst Use Misuse http://www.kidney.de/pget.php?&tw=1&pmid=32657207 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32657207 #FOAvip English Wikipedia <ref>{{Cite pmid|32657207}}</ref> Opioid Use Disorder and COVID-19: Biological Plausibility for Worsened Outcomes #MMPMID32657207 Schimmel J; Manini AF Subst Use Misuse 2020[]; 55 (11): 1900-1901 PMID32657207show ga Alarms have been raised that COVID-19 may disproportionately affect certain populations with substance use disorders, particularly Opioid Use Disorder (OUD), however warnings have largely focused on social risks such as reduced availability of services. Objectives: This commentary highlights three plausible biological mechanisms for potentially worsened outcomes in patients with OUD who contract COVID-19. Results: Opioid-related respiratory depression may amplify risks of hypoxemia from COVID-19 viral pneumonia. Complex opioid immune modulation may impact host response to COVID-19, though the effect direction and clinical significance are unclear. Drug-drug interactions may affect individuals with OUD who are co-administered medications for OUD and medications for COVID-19, particularly due to cardiac adverse effects. Conclusions/Importance: There are plausible biological mechanisms for potentially worsened outcomes in patients with OUD who contract COVID-19; these mechanisms require further study, and should be considered in individuals with OUD. |Adaptive Immunity/immunology[MESH] |Analgesics, Opioid/*adverse effects/therapeutic use[MESH] |Arrhythmias, Cardiac/*chemically induced[MESH] |Betacoronavirus[MESH] |COVID-19[MESH] |Coronavirus Infections/*complications/drug therapy/immunology/physiopathology[MESH] |Drug Interactions[MESH] |Humans[MESH] |Immunity, Innate/immunology[MESH] |Immunocompromised Host/*immunology[MESH] |Methadone/adverse effects[MESH] |Opioid-Related Disorders/*complications/drug therapy/immunology[MESH] |Pandemics[MESH] |Pneumonia, Viral/*complications/drug therapy/immunology/physiopathology[MESH] |Prognosis[MESH] |Respiratory Insufficiency/*chemically induced/physiopathology[MESH]Opioid Use Disorder and COVID-19: Biological Plausibility for Worsened(epmc).pdf DeepDyve Pubget Overpricing