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10.1080/14789450.2020.1794831 http://scihub22266oqcxt.onion/10.1080/14789450.2020.1794831 32654533!ä!32654533 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Expert+Rev+Proteomics 2020 ; 17 (6): 425-432 Nephropedia Template TP {{tp|p=32654533|t=2020. Design of engineered surfaces for prospective detection of SARS-CoV-2 using quartz crystal microbalance-based techniques |pdf=|usr=}}{{32654533}} gab.com Text Design of engineered surfaces for prospective detection of SARS-CoV-2 using quartz crystal microbalance-based techniques JO: Expert Rev Proteomics http://www.kidney.de/pget.php?&tw=1&pmid=32654533 #FOAvip INTRODUCTION: Rapid transmission of the severe acute respiratory syndrome coronavirus 2 has affected the whole world and forced it to a halt (lockdown). A fast and label-free detection method for the novel coronavirus needs to be developed along with the existing enzyme-linked immunosorbent assay (ELISA) and reverse transcription polymerase chain reaction (RT-PCR)-based methods. AREAS COVERED: In this report, biophysical aspects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein are outlined based on its recent reported electron microscopy structure. Protein binding sites are analyzed theoretically, which consisted of hydrophobic and positive charged amino acid residues. Different strategies to form mixed self-assembled monolayers (SAMs) of hydrophobic (CH(3)) and negatively charged (COOH) groups are discussed to be used for the specific and strong interactions with spike protein. Bio-interfacial interactions between the spike protein and device (sensor) surface and its implications toward designing suitable engineered surfaces are summarized. EXPERT OPINION: Implementation of the engineered surfaces in quartz crystal microbalance (QCM)-based detection techniques for the diagnosis of the novel coronavirus from oral swab samples is highlighted. The proposed strategy can be explored for the label-free and real-time detection with sensitivity up to ng level. These engineered surfaces can be reused after desorption. Twit Text FOAVip Design of engineered surfaces for prospective detection of SARS-CoV-2 using quartz crystal microbalance-based techniques ????Expert Rev Proteomics http://www.kidney.de/pget.php?&tw=1&pmid=32654533 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32654533 #FOAvip English Wikipedia <ref>{{Cite pmid|32654533}}</ref> Design of engineered surfaces for prospective detection of SARS-CoV-2 using quartz crystal microbalance-based techniques #MMPMID32654533 Pandey LM Expert Rev Proteomics 2020[Jun]; 17 (6): 425-432 PMID32654533show ga INTRODUCTION: Rapid transmission of the severe acute respiratory syndrome coronavirus 2 has affected the whole world and forced it to a halt (lockdown). A fast and label-free detection method for the novel coronavirus needs to be developed along with the existing enzyme-linked immunosorbent assay (ELISA) and reverse transcription polymerase chain reaction (RT-PCR)-based methods. AREAS COVERED: In this report, biophysical aspects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein are outlined based on its recent reported electron microscopy structure. Protein binding sites are analyzed theoretically, which consisted of hydrophobic and positive charged amino acid residues. Different strategies to form mixed self-assembled monolayers (SAMs) of hydrophobic (CH(3)) and negatively charged (COOH) groups are discussed to be used for the specific and strong interactions with spike protein. Bio-interfacial interactions between the spike protein and device (sensor) surface and its implications toward designing suitable engineered surfaces are summarized. EXPERT OPINION: Implementation of the engineered surfaces in quartz crystal microbalance (QCM)-based detection techniques for the diagnosis of the novel coronavirus from oral swab samples is highlighted. The proposed strategy can be explored for the label-free and real-time detection with sensitivity up to ng level. These engineered surfaces can be reused after desorption. |Betacoronavirus/*chemistry/immunology/metabolism[MESH] |Binding Sites[MESH] |COVID-19 Testing[MESH] |COVID-19 Vaccines[MESH] |Clinical Laboratory Techniques/instrumentation/*methods[MESH] |Coronavirus Infections/diagnosis[MESH] |Humans[MESH] |Hydrophobic and Hydrophilic Interactions[MESH] |Limit of Detection[MESH] |Microscopy, Atomic Force[MESH] |Protein Conformation[MESH] |Quartz Crystal Microbalance Techniques/*instrumentation/methods[MESH] |SARS-CoV-2[MESH] |Spectroscopy, Fourier Transform Infrared[MESH] |Spike Glycoprotein, Coronavirus/*chemistry/immunology/metabolism[MESH]Design of engineered surfaces for prospective detection of SARS-CoV-2 (epmc).pdf DeepDyve Pubget Overpricing