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10.1111/tid.13406 http://scihub22266oqcxt.onion/10.1111/tid.13406 32654357!7404525!32654357     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Transpl+Infect+Dis 2020 ; 22 (5): e13406 Nephropedia Template TP {{tp|p=32654357|t=2020. Low rate of COVID-19 pneumonia in kidney transplant recipients-A battle between infection and immune response?|pdf=|usr=}}{{32654357}} gab.com Text Low rate of COVID-19 pneumonia in kidney transplant recipients-A battle between infection and immune response JO: Transpl Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32654357 #FOAvip BACKGROUND: With COVID-19 pandemic, concerns about kidney transplant recipients are rising. However, the incidence, clinical course, outcome, and predictive factors of disease severity are obscured. METHODS: We describe clinical and laboratory manifestations, radiologic findings, clinical course, and finally outcome of kidney transplant recipients with COVID-19 pneumonia. RESULTS: Of 2493 kidney transplant recipients under follow-up in our clinic, 19 cases (4 cases diagnosed based on radiologic findings) were admitted. The mean age of patients was 47.6 +/- 12.4 years, and the mean time from transplantation was 115.6 +/- 70.3 months. Lymphopenia and eosinopenia were 84.2% and 78.9%, respectively. Nine patients did not survive the hospital course. History of acute rejection during the past 12 months, diabetes, higher N/L ratio, lower platelet count, elevated N/L x CRP, higher levels of LDH, positive D-dimer, higher troponin, and prolonged PT were associated with mortality. Among patients with positive COVID-19 test, history of acute rejection, low platelet count, and positive D-dimer were associated with poor outcome. Treatment with cyclosporine was associated with better clinical outcome. CONCLUSIONS: Low rate of admission in transplant recipients specially in the very first years of transplantation might be due to protective effects of immunosuppressive agents against cytokine storm or modification of immunity function. We suggest evaluation of T-cell number, function, and cytokine profile as a guide to manage COVID-19 mainly in patients with higher risk of mortality. Twit Text FOAVip Low rate of COVID-19 pneumonia in kidney transplant recipients-A battle between infection and immune response ????Transpl Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32654357 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32654357 #FOAvip English Wikipedia <ref>{{Cite pmid|32654357}}</ref> Low rate of COVID-19 pneumonia in kidney transplant recipients-A battle between infection and immune response? #MMPMID32654357 Ghaffari Rahbar M; Nafar M; Khoshdel A; Dalili N; Abrishami A; Firouzan A; Poorrezagholi F; Samadian F; Ziaie S; Fatemizadeh S; Samavat S Transpl Infect Dis 2020[Oct]; 22 (5): e13406 PMID32654357show ga BACKGROUND: With COVID-19 pandemic, concerns about kidney transplant recipients are rising. However, the incidence, clinical course, outcome, and predictive factors of disease severity are obscured. METHODS: We describe clinical and laboratory manifestations, radiologic findings, clinical course, and finally outcome of kidney transplant recipients with COVID-19 pneumonia. RESULTS: Of 2493 kidney transplant recipients under follow-up in our clinic, 19 cases (4 cases diagnosed based on radiologic findings) were admitted. The mean age of patients was 47.6 +/- 12.4 years, and the mean time from transplantation was 115.6 +/- 70.3 months. Lymphopenia and eosinopenia were 84.2% and 78.9%, respectively. Nine patients did not survive the hospital course. History of acute rejection during the past 12 months, diabetes, higher N/L ratio, lower platelet count, elevated N/L x CRP, higher levels of LDH, positive D-dimer, higher troponin, and prolonged PT were associated with mortality. Among patients with positive COVID-19 test, history of acute rejection, low platelet count, and positive D-dimer were associated with poor outcome. Treatment with cyclosporine was associated with better clinical outcome. CONCLUSIONS: Low rate of admission in transplant recipients specially in the very first years of transplantation might be due to protective effects of immunosuppressive agents against cytokine storm or modification of immunity function. We suggest evaluation of T-cell number, function, and cytokine profile as a guide to manage COVID-19 mainly in patients with higher risk of mortality. |Adult[MESH] |Aged[MESH] |Antiviral Agents/therapeutic use[MESH] |COVID-19 Drug Treatment[MESH] |COVID-19/complications/diagnosis/*epidemiology/immunology[MESH] |Cytokine Release Syndrome/diagnosis/*epidemiology/immunology/virology[MESH] |Cytokines/blood/immunology[MESH] |Female[MESH] |Follow-Up Studies[MESH] |Graft Rejection/epidemiology/*immunology/prevention & control[MESH] |Humans[MESH] |Immunity/drug effects[MESH] |Immunocompromised Host[MESH] |Immunosuppressive Agents/*therapeutic use[MESH] |Iran/epidemiology[MESH] |Kidney Transplantation/*adverse effects[MESH] |Lung/diagnostic imaging[MESH] |Lymphocyte Count[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |SARS-CoV-2/immunology/isolation & purification[MESH] |T-Lymphocytes/immunology[MESH] |Tomography, X-Ray Computed[MESH]Low rate of COVID-19 pneumonia in kidney transplant recipients-A battl(epmc).pdf DeepDyve Pubget Overpricing