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10.1002/cyto.a.24188

http://scihub22266oqcxt.onion/10.1002/cyto.a.24188
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32654350!7404377!32654350
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suck abstract from ncbi


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pmid32654350      Cytometry+A 2020 ; 97 (9): 887-890
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  • Decrease of Non-Classical and Intermediate Monocyte Subsets in Severe Acute SARS-CoV-2 Infection #MMPMID32654350
  • Gatti A; Radrizzani D; Vigano P; Mazzone A; Brando B
  • Cytometry A 2020[Sep]; 97 (9): 887-890 PMID32654350show ga
  • In patients with severe SARS-CoV-2 infection, the development of cytokine storm induces extensive lung damage, and monocytes play a role in this pathological process. Non-classical (NC) and intermediate (INT) monocytes are known to be involved during viral and bacterial infections. In this study, 30 patients with different manifestations of acute SARS-CoV-2 infection were investigated with a flow cytometric study of NC, INT, and classical (CL) monocytes. Significantly reduced NC and INT monocytes and a downregulated HLA-DR were found in acute patients with severe SARS-CoV-2 symptoms. Conversely in patients with moderate symptoms NC and INT monocytes and CD11b expression were increased. (c) 2020 International Society for Advancement of Cytometry.
  • |Aged[MESH]
  • |Betacoronavirus/*immunology/pathogenicity[MESH]
  • |Biomarkers/analysis[MESH]
  • |CD11b Antigen/analysis[MESH]
  • |COVID-19[MESH]
  • |Cell Separation[MESH]
  • |Coronavirus Infections/diagnosis/*immunology/virology[MESH]
  • |Female[MESH]
  • |Flow Cytometry[MESH]
  • |Host Microbial Interactions[MESH]
  • |Humans[MESH]
  • |Leukocytes[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Monocytes/*immunology/virology[MESH]
  • |Pandemics[MESH]
  • |Phenotype[MESH]
  • |Pneumonia, Viral/diagnosis/*immunology/virology[MESH]
  • |SARS-CoV-2[MESH]


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