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10.1016/j.mehy.2020.110081

http://scihub22266oqcxt.onion/10.1016/j.mehy.2020.110081
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32653736!7340033!32653736
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suck abstract from ncbi


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pmid32653736      Med+Hypotheses 2020 ; 143 (ä): 110081
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  • Surfactant-based prophylaxis and therapy against COVID-19: A possibility #MMPMID32653736
  • Pramod K; Kotta S; Jijith US; Aravind A; Abu Tahir M; Manju CS; Gangadharappa HV
  • Med Hypotheses 2020[Oct]; 143 (ä): 110081 PMID32653736show ga
  • Hand hygiene by washing with soap and water is recommended for the prevention of COVID-19 spread. Soaps and detergents are explained to act by damaging viral spike glycoproteins (peplomers) or by washing out the virus through entrapment in the micelles. Technically, soaps come under a functional category of molecules known as surfactants. Surfactants are widely used in pharmaceutical formulations as excipients. We wonder why surfactants are still not tried for prophylaxis or therapy against COVID-19? That too when many of them have proven antiviral properties. Moreover, lung surfactants have already shown benefits in respiratory viral infections. Therefore, we postulate that surfactant-based prophylaxis and therapy would be promising. We believe that our hypothesis would stimulate debate or new research exploring the possibility of surfactant-based prophylaxis and therapy against COVID-19. The success of a surfactant-based technique would save the world from any such pandemic in the future too.
  • |*Betacoronavirus/drug effects[MESH]
  • |Antiviral Agents/administration & dosage/pharmacology[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Coronavirus Infections/*drug therapy/*prevention & control/transmission[MESH]
  • |Humans[MESH]
  • |Micelles[MESH]
  • |Models, Biological[MESH]
  • |Mouthwashes/administration & dosage/pharmacology[MESH]
  • |Pandemics/*prevention & control[MESH]
  • |Pneumonia, Viral/*drug therapy/*prevention & control/transmission[MESH]
  • |SARS-CoV-2[MESH]


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